Modular and Versatile Trans-Encoded Genetic Switches
| dc.bibliographicCitation.firstPage | 20328 | eng |
| dc.bibliographicCitation.issue | 46 | eng |
| dc.bibliographicCitation.journalTitle | Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker : International edition | eng |
| dc.bibliographicCitation.lastPage | 20332 | eng |
| dc.bibliographicCitation.volume | 59 | eng |
| dc.contributor.author | Paul, Avishek | |
| dc.contributor.author | Warszawik, Eliza M. | |
| dc.contributor.author | Loznik, Mark | |
| dc.contributor.author | Boersma, Arnold J. | |
| dc.contributor.author | Herrmann, Andreas | |
| dc.date.accessioned | 2021-07-30T06:26:13Z | |
| dc.date.available | 2021-07-30T06:26:13Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | Current bacterial RNA switches suffer from lack of versatile inputs and are difficult to engineer. We present versatile and modular RNA switches that are trans-encoded and based on tRNA-mimicking structures (TMSs). These switches provide a high degree of freedom for reengineering and can thus be designed to accept a wide range of inputs, including RNA, small molecules, and proteins. This powerful approach enables control of the translation of protein expression from plasmid and genome DNA. © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA | eng |
| dc.description.version | publishedVersion | eng |
| dc.identifier.uri | https://oa.tib.eu/renate/handle/123456789/6437 | |
| dc.identifier.uri | https://doi.org/10.34657/5484 | |
| dc.language.iso | eng | eng |
| dc.publisher | Weinheim : Wiley-VCH | eng |
| dc.relation.doi | https://doi.org/10.1002/anie.202001372 | |
| dc.relation.essn | 1521-3773 | |
| dc.relation.issn | 0570-0833 | |
| dc.relation.issn | 1433-7851 | |
| dc.rights.license | CC BY 4.0 Unported | eng |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | eng |
| dc.subject.ddc | 540 | eng |
| dc.subject.other | RNA | eng |
| dc.subject.other | RNA logic gates | eng |
| dc.subject.other | RNA switches | eng |
| dc.subject.other | synthetic biology | eng |
| dc.title | Modular and Versatile Trans-Encoded Genetic Switches | eng |
| dc.type | Article | eng |
| dc.type | Text | eng |
| tib.accessRights | openAccess | eng |
| wgl.contributor | DWI | eng |
| wgl.subject | Chemie | eng |
| wgl.type | Zeitschriftenartikel | eng |
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