High-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cells
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144
Issue
15
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Analyst
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Cambridge : Royal Society of Chemistry
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Abstract
High-throughput screening Raman spectroscopy (HTS-RS) with automated localization algorithms offers unsurpassed speed and sensitivity to investigate the effect of dithiothreitol on the diatom Phaedactylum tricornutum. The HTS-RS capability that was demonstrated for this model system can be transferred to unmet analytical applications such as kinetic in vivo studies of microalgal assemblages. © 2019 The Royal Society of Chemistry.
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Keywords
diadinoxanthin, diatoxanthin, dithiothreitol, fucoxanthin, xanthophyll, algorithm, chemistry, diatom, drug effect, high throughput screening, light, metabolism, procedures, radiation response, Raman spectrometry, Algorithms, Diatoms, Dithiothreitol, High-Throughput Screening Assays, Light, Spectrum Analysis, Raman, Xanthophylls
Keywords GND
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CC BY-NC 3.0 Unported