This document may be downloaded, read, stored and printed for your own use within the limits of § 53 UrhG but it may not be distributed via the internet or passed on to external parties.Dieses Dokument darf im Rahmen von § 53 UrhG zum eigenen Gebrauch kostenfrei heruntergeladen, gelesen, gespeichert und ausgedruckt, aber nicht im Internet bereitgestellt oder an Außenstehende weitergegeben werden.Fasano, AntonioHömberg, DietmarNaumov, Dmitri2016-03-242019-06-2820080946-8633https://doi.org/10.34657/2782https://oa.tib.eu/renate/handle/123456789/2044We study a mathematical model for laser-induced thermotherapy, a minimally invasive cancer treatment. The model consists of a diffusion approximation of the radiation transport equation coupled to a bio-heat equation and a model to describe the evolution of the coagulated zone. Special emphasis is laid on a refined model of the applicator device, accounting for the effect of coolant flow inside. Comparisons between experiment and simulations show that the model is able to predict the experimentally achieved temperatures reasonably well.application/pdfeng510Laser treatmentcancer therapycoagulationbio-heat equationReport