CC BY-NC-ND 4.0 UnportedGruetzmacher, KimKaresh, William B.Amuasi, John H.Arshad, AdnanFarlow, AndrewGabrysch, SabineJetzkowitz, JensLieberman, SusanPalmer, ClareWinkler, Andrea S.Walzer, Chris2022-05-102022-05-102020https://oa.tib.eu/renate/handle/123456789/8927https://doi.org/10.34657/7965For over 15-years, proponents of the One Health approach have worked to consistently interweave components that should never have been separated and now more than ever need to be re-connected: the health of humans, non-human animals, and ecosystems. We have failed to heed the warning signs. A One Health approach is paramount in directing our future health in this acutely and irrevocably changed world. COVID-19 has shown us the exorbitant cost of inaction. The time to act is now. © 2020enghttps://creativecommons.org/licenses/by-nc-nd/4.0/333,7610Berlin principlesHolistic health approachIntegrated health approachManhattan principlesOne healthPlanetary healthArticle