CC BY-NC 3.0 UnportedRüger J.Mondol A.S.Schie I.W.Popp J.Krafft C.2021-09-072021-09-072019https://oa.tib.eu/renate/handle/123456789/6738https://doi.org/10.34657/5785High-throughput screening Raman spectroscopy (HTS-RS) with automated localization algorithms offers unsurpassed speed and sensitivity to investigate the effect of dithiothreitol on the diatom Phaedactylum tricornutum. The HTS-RS capability that was demonstrated for this model system can be transferred to unmet analytical applications such as kinetic in vivo studies of microalgal assemblages. © 2019 The Royal Society of Chemistry.enghttps://creativecommons.org/licenses/by-nc/3.0/540diadinoxanthindiatoxanthindithiothreitolfucoxanthinxanthophyllalgorithmchemistrydiatomdrug effecthigh throughput screeninglightmetabolismproceduresradiation responseRaman spectrometryAlgorithmsDiatomsDithiothreitolHigh-Throughput Screening AssaysLightSpectrum Analysis, RamanXanthophyllsHigh-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cellsArticle