Browsing by Author "Liu, Jujun"
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- ItemIdentification of the thermal growth characteristics of coagulated tumor tissue in laser-induced thermotherapy(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2011) Hömberg, Dietmar; Liu, Jujun; Togobytska, NataliyaWe consider an inverse problem arising in laser-induced thermotherapy, a minimally invasive method for cancer treatment, in which cancer tissues is destroyed by coagulation. For the dosage planning numerical simulation play an important role. To this end a crucial problem is to identify the thermal growth kinetics of the coagulated zone. Mathematically, this problem is a nonlinear and nonlocal parabolic heat source inverse problem. The solution to this inverse problem is defined as the minimizer of a nonconvex cost functional. The existence of the minimizer is proven. We derive the Gateaux derivative of the cost functional, which is based on the adjoint system, and use it for a numerical approximation of the optimal coefficient.