Laccase-catalyzed derivatization of antibiotics with sulfonamide or sulfone structures
| dc.bibliographicCitation.firstPage | 2199 | |
| dc.bibliographicCitation.issue | 11 | |
| dc.bibliographicCitation.journalTitle | Microorganisms | eng |
| dc.bibliographicCitation.volume | 9 | |
| dc.contributor.author | Mikolasch, Annett | |
| dc.contributor.author | Hahn, Veronika | |
| dc.date.accessioned | 2023-05-22T07:20:03Z | |
| dc.date.available | 2023-05-22T07:20:03Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Trametes spec. laccase (EC 1.10.3.2.) mediates the oxidative coupling of antibiotics with sulfonamide or sulfone structures with 2,5-dihydroxybenzene derivatives to form new heterodimers and heterotrimers. These heteromolecular hybrid products are formed by nuclear amination of the p-hydroquinones with the primary amino group of the sulfonamide or sulfone antibiotics, and they inhibited in vitro the growth of Staphylococcus species, including multidrug-resistant strains. | eng |
| dc.description.version | publishedVersion | eng |
| dc.identifier.uri | https://oa.tib.eu/renate/handle/123456789/12166 | |
| dc.identifier.uri | http://dx.doi.org/10.34657/11199 | |
| dc.language.iso | eng | |
| dc.publisher | Basel : MDPI | |
| dc.relation.doi | https://doi.org/10.3390/microorganisms9112199 | |
| dc.relation.essn | 2076-2607 | |
| dc.rights.license | CC BY 4.0 Unported | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
| dc.subject.ddc | 570 | |
| dc.subject.other | Antibacterial activity | eng |
| dc.subject.other | Antimicrobial resistance (AMR) | eng |
| dc.subject.other | Biotransformation | eng |
| dc.subject.other | Laccase | eng |
| dc.subject.other | Methicillin-resistant Staphylococcus aureus (MRSA) | eng |
| dc.subject.other | Multidrug resistance (MDR) | eng |
| dc.subject.other | Sulfonamide antibiotics | eng |
| dc.subject.other | β-lactam antibiotics | eng |
| dc.title | Laccase-catalyzed derivatization of antibiotics with sulfonamide or sulfone structures | eng |
| dc.type | Article | eng |
| dc.type | Text | eng |
| tib.accessRights | openAccess | |
| wgl.contributor | INP | |
| wgl.subject | Biowissenschaften/Biologie | ger |
| wgl.type | Zeitschriftenartikel | ger |
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