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PTFEP-Al2O3 hybrid nanowires reducing thrombosis and biofouling
2019, Haidar, Ayman, Ali, Awadelkareem A., Veziroglu, Salih, Fiutowski, Jacek, Eichler, Hermann, Müller, Isabelle, Kiefer, Karin, Faupel, Franz, Bischoff, Markus, Veith, Michael, Aktas, Oral Cenk, Abdul-Khaliq, Hashim
Thrombosis and bacterial infection are major problems in cardiovascular implants. Here we demonstrated that a superhydrophobic surface composed of poly(bis(2,2,2-trifluoroethoxy)phosphazene) (PTFEP)-Al2O3 hybrid nanowires (NWs) is effective to reduce both platelet adhesion/activation and bacterial adherence/colonization. The proposed approach allows surface modification of cardiovascular implants which have 3D complex geometries. © 2019 The Royal Society of Chemistry.