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Author: Harazim, Stefan M. × WGL Institute: IFWD ×

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Now showing 1 - 2 of 2
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    Chemotactic behavior of catalytic motors in microfluidic channels
    (Hoboken, NJ : Wiley, 2013) Baraban, Larysa; Harazim, Stefan M.; Sanchez, Samuel; Schmidt, Oliver.G.
    Chemotaxis in practice: Two different artificial catalytic micromotors (tubular and spherical, see scheme) show chemotactic behavior in microfluidic channels demonstrating that catalytic micromotors can sense the gradient of chemical fuel in their environment and be directed towards desired locations.
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    Dimensionality of rolled-up nanomembranes controls neural stem cell migration mechanism
    (Washington D.C. : American Chemical Society, 2015) Koch, Britta; Meyer, Anne K.; Helbig, Linda; Harazim, Stefan M.; Storch, Alexander; Sanchez, Samuel; Schmidt, Oliver G.
    We employ glass microtube structures fabricated by rolledup nanotechnology to infer the influence of scaffold dimensionality and cell confinement on neural stem cell (NSC) migration. Thereby, we observe a pronounced morphology change that marks a reversible mesenchymal to amoeboid migration mode transition. Space restrictions preset by the diameter of nanomembrane topography modify the cell shape toward characteristics found in living tissue. We demonstrate the importance of substrate dimensionality for the migration mode of NSCs and thereby define rolled-up nanomembranes as the ultimate tool for single-cell migration studies.