Filters

2017 - 20182

More filters

20222
Reset filters

Settings

Author: Keul, Helmut × Author: Marquardt, Fabian × Author: Möller, Martin × End date: 2019 × DDC: 540 ×

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Novel Antibacterial Polyglycidols: Relationship between Structure and Properties
    (Basel : MDPI, 2018) Marquardt, Fabian; Stöcker, Cornelia; Gartzen, Rita; Heine, Elisabeth; Keul, Helmut; Möller, Martin
    Antimicrobial polymers are an attractive alternative to low molecular weight biocides, because they are non-volatile, chemically stable, and can be used as non-releasing additives. Polymers with pendant quaternary ammonium groups and hydrophobic chains exhibit antimicrobial properties due to the electrostatic interaction between polymer and cell wall, and the membrane disruptive capabilities of the hydrophobic moiety. Herein, the synthesis of cationic–hydrophobic polyglycidols with varying structures by post-polymerization modification is presented. The antimicrobial properties of the prepared polyglycidols against E. coli and S. aureus are examined. Polyglycidol with statistically distributed cationic and hydrophobic groups (cationic–hydrophobic balance of 1:1) is compared to (i) polyglycidol with a hydrophilic modification at the cationic functionality; (ii) polyglycidol with both—cationic and hydrophobic groups—at every repeating unit; and (iii) polyglycidol with a cationic–hydrophobic balance of 1:2. A relationship between structure and properties is presented.
  • Thumbnail Image
    Item
    Homoserine Lactone as a Structural Key Element for the Synthesis of Multifunctional Polymers
    (Basel : MDPI, 2017) Marquardt, Fabian; Mommer, Stefan; Lange, Justin; Jeschenko, Pascal M.; Keul, Helmut; Möller, Martin
    The use of bio-based building blocks for polymer synthesis represents a milestone on the way to “green” materials. In this work, two synthetic strategies for the preparation of multifunctional polymers are presented in which the key element is the functionality of homoserine lactone. First, the synthesis of a bis cyclic coupler based on a thiolactone and homoserine lactone is displayed. This coupler was evaluated regarding its regioselectivity upon reaction with amines and used in the preparation of multifunctional polymeric building blocks by reaction with diamines. Furthermore, a linear polyglycidol was functionalized with homoserine lactone. The resulting polyethers with lactone groups in the side chain were converted to cationic polymers by reaction with 3-(dimethylamino)-1-propylamine followed by quaternization with methyl iodide.