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A Data-Driven Approach for Analyzing Healthcare Services Extracted from Clinical Records

2020, Scurti, Manuel, Menasalvas-Ruiz, Ernestina, Vidal, Maria-Esther, Torrente, Maria, Vogiatzis, Dimitrios, Paliouras, George, Provencio, Mariano, Rodríguez-González, Alejandro, Seco de Herrera, Alba García, Rodríguez González, Alejandro, Santosh, K.C., Temesgen, Zelalem, Soda, Paolo

Cancer remains one of the major public health challenges worldwide. After cardiovascular diseases, cancer is one of the first causes of death and morbidity in Europe, with more than 4 million new cases and 1.9 million deaths per year. The suboptimal management of cancer patients during treatment and subsequent follows up are major obstacles in achieving better outcomes of the patients and especially regarding cost and quality of life In this paper, we present an initial data-driven approach to analyze the resources and services that are used more frequently by lung-cancer patients with the aim of identifying where the care process can be improved by paying a special attention on services before diagnosis to being able to identify possible lung-cancer patients before they are diagnosed and by reducing the length of stay in the hospital. Our approach has been built by analyzing the clinical notes of those oncological patients to extract this information and their relationships with other variables of the patient. Although the approach shown in this manuscript is very preliminary, it shows that quite interesting outcomes can be derived from further analysis. © 2020 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.

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Calibrating mini-mental state examination scores to predict misdiagnosed dementia patients

2021, Vyas, Akhilesh, Aisopos, Fotis, Vidal, Maria-Esther, Garrard, Peter, Paliouras, George

Mini-Mental State Examination (MMSE) is used as a diagnostic test for dementia to screen a patient’s cognitive assessment and disease severity. However, these examinations are often inaccurate and unreliable either due to human error or due to patients’ physical disability to correctly interpret the questions as well as motor deficit. Erroneous data may lead to a wrong assessment of a specific patient. Therefore, other clinical factors (e.g., gender and comorbidities) existing in electronic health records, can also play a significant role, while reporting her examination results. This work considers various clinical attributes of dementia patients to accurately determine their cognitive status in terms of the Mini-Mental State Examination (MMSE) Score. We employ machine learning models to calibrate MMSE score and classify the correctness of diagnosis among patients, in order to assist clinicians in a better understanding of the progression of cognitive impairment and subsequent treatment. For this purpose, we utilize a curated real-world ageing study data. A random forest prediction model is employed to estimate the Mini-Mental State Examination score, related to the diagnostic classification of patients.This model uses various clinical attributes to provide accurate MMSE predictions, succeeding in correcting an important percentage of cases that contain previously identified miscalculated scores in our dataset. Furthermore, we provide an effective classification mechanism for automatically identifying patient episodes with inaccurate MMSE values with high confidence. These tools can be combined to assist clinicians in automatically finding episodes within patient medical records where the MMSE score is probably miscalculated and estimating what the correct value should be. This provides valuable support in the decision making process for diagnosing potential dementia patients.