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Biofunctionalized self-propelled micromotors as an alternative on-chip concentrating system

2014, Restrepo-Pérez, Laura, Meyer, Anne K., Helbig, Linda, Sanchez, Samuel, Schmidt, Oliver G.

Sample pre-concentration is crucial to achieve high sensitivity and low detection limits in lab-on-a-chip devices. Here, we present a system in which self-propelled catalytic micromotors are biofunctionalized and trapped acting as an alternative concentrating mechanism. This system requires no external energy source, which facilitates integration and miniaturization.

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Thermal activation of catalytic microjets in blood samples using microfluidic chips

2013, Restrepo-Pérez, Laura, Soler, Lluís, Martínez-Cisneros, Cynthia S., Sanchez, Samuel, Schmidt, Oliver G.

We demonstrate that catalytic microjet engines can out-swim high complex media composed of red blood cells and serum. Despite the challenge presented by the high viscosity of the solution at room temperature, the catalytic microjets can be activated at physiological temperature and, consequently, self-propel in diluted solutions of blood samples. We prove that these microjets self-propel in 10× diluted blood samples using microfluidic chips.