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A Rotating Spiral Micromotor for Noninvasive Zygote Transfer
Embryo transfer (ET) is a decisive step in the in vitro fertilization process. In most cases, the embryo is transferred to the uterus after several days of in vitro culture. Although studies have identified the beneficial effects of ET on proper embryo development in the earlier stages, this strategy is compromised by the necessity to transfer early embryos (zygotes) back to the fallopian tube instead of the uterus, which requires a more invasive, laparoscopic procedure, termed zygote intrafallopian transfer (ZIFT). Magnetic micromotors offer the possibility to mitigate such surgical interventions, as they have the potential to transport and deliver cellular cargo such as zygotes through the uterus and fallopian tube noninvasively, actuated by an externally applied rotating magnetic field. This study presents the capture, transport, and release of bovine and murine zygotes using two types of magnetic micropropellers, helix and spiral. Although helices represent an established micromotor architecture, spirals surpass them in terms of motion performance and with their ability to reliably capture and secure the cargo during both motion and transfer between different environments. Herein, this is demonstrated with murine oocytes/zygotes as the cargo; this is the first step toward the application of noninvasive, magnetic micromotor‐assisted ZIFT.
Stress‐Actuated Spiral Microelectrode for High‐Performance Lithium‐Ion Microbatteries
Miniaturization of batteries lags behind the success of modern electronic devices. Neither the device volume nor the energy density of microbatteries meets the requirement of microscale electronic devices. The main limitation for pushing the energy density of microbatteries arises from the low mass loading of active materials. However, merely pushing the mass loading through increased electrode thickness is accompanied by the long charge transfer pathway and inferior mechanical properties for long‐term operation. Here, a new spiral microelectrode upon stress‐actuation accomplishes high mass loading but short charge transfer pathways. At a small footprint area of around 1 mm2, a 21‐fold increase of the mass loading is achieved while featuring fast charge transfer at the nanoscale. The spiral microelectrode delivers a maximum area capacity of 1053 µAh cm−2 with a retention of 67% over 50 cycles. Moreover, the energy density of the cylinder microbattery using the spiral microelectrode as the anode reaches 12.6 mWh cm−3 at an ultrasmall volume of 3 mm3. In terms of the device volume and energy density, the cylinder microbattery outperforms most of the current microbattery technologies, and hence provides a new strategy to develop high‐performance microbatteries that can be integrated with miniaturized electronic devices.
Steering Directional Light Emission and Mode Chirality through Postshaping of Cavity Geometry
Dielectric optical microcavities have been explored as an excellent platform to manipulate the light flow and investigate non‐Hermitian physics in open optical systems. For whispering gallery mode optical microcavities, modifying the rotational symmetry is highly desirable for intriguing phenomena such as degenerated chiral modes and directional light emission. However, for the state‐of‐the‐art approaches, namely deforming the cavity geometry by precision lithography or introducing local scatterers near the cavity boundary via micromanipulation, there is a lack of flexibility in fine‐adjusting of chiral symmetry and far‐field emission direction. Here, precise engineering of cavity boundary using electron‐beam‐induced deposition is reported based on rolled‐up nanomembrane‐enabled spiral‐shaped microcavities. The deformation of outer boundary results in delicate tailoring of asymmetric backscattering between the outer and inner rolling edges, and hence deterministically strong mode chirality. Besides, the crescent‐shaped high‐index nanocap leads to modified light tunneling channels and inflected far‐field emission angle. It is envisioned that such a localized deposition‐assisted technique for adjusting the structural deformation of 3D optical microcavities will be highly useful for understanding rich insights in non‐Hermitian photonics and unfolding exotic properties on lasing, sensing, and cavity quantum electrodynamics.
Quantum dot-based broadband optical antenna for efficient extraction of single photons in the telecom O-band
Long-distance fiber-based quantum communication relies on efficient non-classical light sources operating at telecommunication wavelengths. Semiconductor quantum dots are promising candidates for on-demand generation of single photons and entangled photon pairs for such applications. However, their brightness is strongly limited due to total internal reflection at the semiconductor/vacuum interface. Here we overcome this limitation using a dielectric antenna structure. The non-classical light source consists of a gallium phosphide solid immersion lens in combination with a quantum dot nanomembrane emitting single photons in the telecom O-band. With this device, the photon extraction is strongly increased in a broad spectral range. A brightness of 17% (numerical aperture of 0.6) is obtained experimentally, with a single photon purity of 𝑔(2)(0)=0.049±0.02 at saturation power. This brings the practical implementation of quantum communication networks one step closer.
Stamping Fabrication of Flexible Planar Micro‐Supercapacitors Using Porous Graphene Inks
High performance, flexibility, safety, and robust integration for micro‐supercapacitors (MSCs) are of immense interest for the urgent demand for miniaturized, smart energy‐storage devices. However, repetitive photolithography processes in the fabrication of on‐chip electronic components including various photoresists, masks, and toxic etchants are often not well‐suited for industrial production. Here, a cost‐effective stamping strategy is developed for scalable and rapid preparation of graphene‐based planar MSCs. Combining stamps with desired shapes and highly conductive graphene inks, flexible MSCs with controlled structures are prepared on arbitrary substrates without any metal current collectors, additives, and polymer binders. The interdigitated MSC exhibits high areal capacitance up to 21.7 mF cm−2 at a current of 0.5 mA and a high power density of 6 mW cm−2 at an energy density of 5 µWh cm−2. Moreover, the MSCs show outstanding cycling performance and remarkable flexibility over 10 000 charge–discharge cycles and 300 bending cycles. In addition, the capacitance and output voltage of the MSCs are easily adjustable through interconnection with well‐defined arrangements. The efficient, rapid manufacturing of the graphene‐based interdigital MSCs with outstanding flexibility, shape diversity, and high areal capacitance shows great potential in wearable and portable electronics.
Towards Bacteria Counting in DI Water of Several Microliters or Growing Suspension Using Impedance Biochips
We counted bacterial cells of E. coli strain K12 in several-microliter DI water or in several-microliter PBS in the low optical density (OD) range (OD = 0.05–1.08) in contact with the surface of Si-based impedance biochips with ring electrodes by impedance measurements. The multiparameter fit of the impedance data allowed calibration of the impedance data with the concentration cb of the E. coli cells in the range of cb = 0.06 to 1.26 × 109 cells/mL. The results showed that for E. coli in DI water and in PBS, the modelled impedance parameters depend linearly on the concentration of cells in the range of cb = 0.06 to 1.26 × 109 cells/mL, whereas the OD, which was independently measured with a spectrophotometer, was only linearly dependent on the concentration of the E. coli cells in the range of cb = 0.06 to 0.50 × 109 cells/mL.
Large-range frequency tuning of a narrow-linewidth quantum emitter
A hybrid system of a semiconductor quantum dot single photon source and a rubidium quantum memory represents a promising architecture for future photonic quantum repeaters. One of the key challenges lies in matching the emission frequency of quantum dots with the transition frequency of rubidium atoms while preserving the relevant emission properties. Here, we demonstrate the bidirectional frequency tuning of the emission from a narrow-linewidth (close-to-transform-limited) quantum dot. The frequency tuning is based on a piezoelectric strain-amplification device, which can apply significant stress to thick bulk samples. The induced strain shifts the emission frequency of the quantum dot over a total range of 1.15 THz, about three orders of magnitude larger than its linewidth. Throughout the whole tuning process, both the spectral properties of the quantum dot and its single-photon emission characteristics are preserved. Our results show that external stress can be used as a promising tool for reversible frequency tuning of high-quality quantum dots and pave the wave toward the realization of a quantum dot–rubidium atom interface for quantum networking.
Selective Out‐of‐Plane Optical Coupling between Vertical and Planar Microrings in a 3D Configuration
3D photonic integrated circuits are expected to play a key role in future optoelectronics with efficient signal transfer between photonic layers. Here, the optical coupling of tubular microcavities, supporting resonances in a vertical plane, with planar microrings, accommodating in‐plane resonances, is explored. In such a 3D coupled composite system with largely mismatched cavity sizes, periodic mode splitting and resonant mode shifts are observed due to mode‐selective interactions. The axial direction of the microtube cavity provides additional design freedom for selective mode coupling, which is achieved by carefully adjusting the axial displacement between the microtube and the microring. The spectral anticrossing behavior is caused by strong coupling in this composite optical system and is excellently reproduced by numerical modeling. Interfacing tubular microcavities with planar microrings is a promising approach toward interlayer light transfer with added optical functionality in 3D photonic systems.
Engineering microrobots for targeted cancer therapies from a medical perspective
Systemic chemotherapy remains the backbone of many cancer treatments. Due to its untargeted nature and the severe side effects it can cause, numerous nanomedicine approaches have been developed to overcome these issues. However, targeted delivery of therapeutics remains challenging. Engineering microrobots is increasingly receiving attention in this regard. Their functionalities, particularly their motility, allow microrobots to penetrate tissues and reach cancers more efficiently. Here, we highlight how different microrobots, ranging from tailor-made motile bacteria and tiny bubble-propelled microengines to hybrid spermbots, can be engineered to integrate sophisticated features optimised for precision-targeting of a wide range of cancers. Towards this, we highlight the importance of integrating clinicians, the public and cancer patients early on in the development of these novel technologies.
3D Self‐Assembled Microelectronic Devices: Concepts, Materials, Applications
Modern microelectronic systems and their components are essentially 3D devices that have become smaller and lighter in order to improve performance and reduce costs. To maintain this trend, novel materials and technologies are required that provide more structural freedom in 3D over conventional microelectronics, as well as easier parallel fabrication routes while maintaining compatability with existing manufacturing methods. Self‐assembly of initially planar membranes into complex 3D architectures offers a wealth of opportunities to accommodate thin‐film microelectronic functionalities in devices and systems possessing improved performance and higher integration density. Existing work in this field, with a focus on components constructed from 3D self‐assembly, is reviewed, and an outlook on their application potential in tomorrow's microelectronics world is provided.