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- ItemMagnetooptical response of permalloy multilayer structures on different substrate in the IR-VIS-UV spectral range(Bristol : IOP Publ., 2019) Patra, Rajkumar; Mattheis, Roland; Stöcker, Hartmut; Monecke, Manuel; Salvan, Georgeta; Schäfer, Rudolf; Schmidt, Oliver G.; Schmidt, HeidemarieThe magnetooptical (MO) response of Ru/Py/Ta thin film stacks with 4, 8, and 17 nm thick Ni81Fe19 permalloy (Py) films on a SiO2/Si and a ZnO substrate was measured by vector magnetooptical generalized ellipsometry. The MO response from VMOGE was modelled using a 4 × 4 Mueller matrix algorithm. The wavelength-dependent, substrate-independent and thickness-independent complex MO coupling constant (Q) of Py in the Ru/Py/Ta thin film stacks was extracted by fitting Mueller matrix difference spectra in the spectral range from 300 nm to 1000 nm. Although the composition-dependent saturation magnetization of NixFe1−x alloys (x = 0.0...1.0), e.g. of Ni81Fe19, is predictable from the two saturation magnetization end points, the MO coupling constant of NixFe1−x is not predictable from the two Q end points. However, in a small alloy range (0.0 < x < 0.2 and 0.8 < x < 1.0) the composition-dependent Q of NixFe1−x can be interpolated from a sufficiently high number of analyzed NixFe1−x alloys. The available complex MO coupling constants of six different NixFe1−x (x = 1.0 to 0.0) alloys were used to interpolate MO response of binary NixFe1−x alloys in the range from x = 0.0 to x = 1.0.
- ItemReal-Time IR Tracking of Single Reflective Micromotors through Scattering Tissues(Weinheim : Wiley-VCH, 2019) Aziz, Azaam; Medina-Sánchez, Mariana; Koukourakis, Nektarios; Wang, Jiawei; Kuschmierz, Robert; Radner, Hannes; Czarske, Jürgen W.; Schmidt, Oliver G.Medical micromotors have the potential to lead to a paradigm shift in future biomedicine, as they may perform active drug delivery, microsurgery, tissue engineering, or assisted fertilization in a minimally invasive manner. However, the translation to clinical treatment is challenging, as many applications of single or few micromotors require real-time tracking and control at high spatiotemporal resolution in deep tissue. Although optical techniques are a popular choice for this task, absorption and strong light scattering lead to a pronounced decrease of the signal-to-noise ratio with increasing penetration depth. Here, a highly reflective micromotor is introduced which reflects more than tenfold the light intensity of simple gold particles and can be precisely navigated by external magnetic fields. A customized optical IR imaging setup and an image correlation technique are implemented to track single micromotors in real-time and label-free underneath phantom and ex vivo mouse skull tissues. As a potential application, the micromotors speed is recorded when moving through different viscous fluids to determine the viscosity of diverse physiological fluids toward remote cardiovascular disease diagnosis. Moreover, the micromotors are loaded with a model drug to demonstrate their cargo-transport capability. The proposed reflective micromotor is suitable as theranostic tool for sub-skin or organ-on-a-chip applications. © 2019 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.