Filters

2017 - 20182

More filters

20232
Reset filters

Settings

Author: Schwarz, Simona × Subject: Polyelectrolyte complexes ×

Search Results

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Effects of (complementary) polyelectrolytes characteristics on composite calcium carbonate microparticles properties
    (Bucureşti : [Verlag nicht ermittelbar], 2017) Mic, Cristian Barbu; Mihai, Marcela; Varganici, Cristian Dragos; Schwarz, Simona; Scutaru, Dan; Simionescu, Bogdan C.
    This study follows the possibility to tune the thermal stability of some CaCO3/polymer composites by crystal growth from supersaturated solutions controlled by polymer structure or by using nonstoichiometric polyelectrolyte complexes (NPECs). As the ratio between the organic and inorganic parts in the composites controls the Ca2+/polymer network crosslinking density, the CaCO3/polymer weight ratio was kept constant at 50/1, varying the initial concentration of the polyanions solutions (0.05 or 0.06 wt.%), the NPECs molar ratio , n+/n- (0.2 or 0.4), or the inorganic precursors concentration (0.25 or 0.3 M). Poly(2-acrylamido-2-methylpropanesulfonic acid-co-acrylic acid) (PSA) and chondroitin-4-sulfate (CSA) were used as polyanions. Some NPEC dispersions, prepared with the same polyanions and poly(allylamine hydrochloride) (PAH), were also used for calcium carbonate crystallization. The characteristics of the prepared composites were investigated by scanning electron microscopy (SEM), flow particle image analysis (FPIA), particles charge density (CD), zeta-potential (ZP). The thermal stability of the composite particles was investigated as compared to bare CaCO3 microparticles prepared at the same initial inorganic concentrations.
  • Thumbnail Image
    Item
    Complex calcium carbonate/polymer microparticles as carriers for aminoglycoside antibiotics
    (London : RSC Publishing, 2018) Racovita, Stefania; Vasiliu, Ana-Lavinia; Bele, Adrian; Schwarz, Dana; Steinbach, Christine; Boldt, Regine; Schwarz, Simona; Mihai, Marcela
    Composite microparticles of CaCO3 and two pectin samples (which differ by the functional group ratio) or corresponding nonstoichiometric polyelectrolyte complexes with different molar ratios (0.5, 0.9 and 1.2) are obtained, characterized and tested for loading and release of streptomycin and kanamycin sulphate. The synthesized carriers were characterized before and after drug loading in terms of morphology (by SEM using secondary electron and energy selective backscattered electron detectors), porosity (by water sorption isotherms) and elemental composition (by elemental mapping using energy dispersive X-ray and FTIR spectroscopy). The kinetics of the release mechanism from the microparticles was investigated using Higuchi and Korsmeyer-Peppas mathematical models.