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- ItemA boundary control problem for the pure Cahn-Hilliard equation with dynamic boundary conditions(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2015) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenA boundary control problem for the pure Cahn-Hilliard equations with possibly singular potentials and dynamic boundary conditions is studied and first-order necessary conditions for optimality are proved.
- ItemOptimal boundary control of a nonstandard Cahn-Hilliard system with dynamic boundary condition and double obstacle inclusions : dedicated to our friend Prof. Dr. Gianni Gilardi on the occasion of his 70th birthday(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2017) Colli, Pierluigi; Sprekels, JürgenIn this paper, we study an optimal boundary control problem for a model for phase separation taking place in a spatial domain that was introduced by P. Podio-Guidugli in Ric. Mat. 55 (2006), pp. 105–118. The model consists of a strongly coupled system of nonlinear parabolic differential inclusions, in which products between the unknown functions and their time derivatives occur that are difficult to handle analytically; the system is complemented by initial and boundary conditions. For the order parameter of the phase separation process, a dynamic boundary condition involving the Laplace–Beltrami operator is assumed, which models an additional nonconserving phase transition occurring on the surface of the domain. We complement in this paper results that were established in the recent contribution appeared in Evol. Equ. Control Theory 6 (2017), pp. 35–58, by the two authors and Gianni Gilardi. In contrast to that paper, in which differentiable potentials of logarithmic type were considered, we investigate here the (more difficult) case of nondifferentiable potentials of double obstacle type. For such nonlinearities, the standard techniques of optimal control theory to establish the existence of Lagrange multipliers for the state constraints are known to fail. To overcome these difficulties, we employ the following line of approach: we use the results contained in the preprint arXiv:1609.07046 [math.AP] (2016), pp. 1–30, for the case of (differentiable) logarithmic potentials and perform a so-called “deep quench limit”. Using compactness and monotonicity arguments, it is shown that this strategy leads to the desired first-order necessary optimality conditions for the case of (nondifferentiable) double obstacle potentials.
- ItemSecond-order analysis of an optimal control problem in a phase field tumor growth model with singular potentials and chemotaxis(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2020) Colli, Pierluigi; Signori, Andrea; Sprekels, JürgenThis paper concerns a distributed optimal control problem for a tumor growth model of Cahn--Hilliard type including chemotaxis with possibly singular anpotentials, where the control and state variables are nonlinearly coupled. First, we discuss the weak well-posedness of the system under very general assumptions for the potentials, which may be singular and nonsmooth. Then, we establish the strong well-posedness of the system in a reduced setting, which however admits the logarithmic potential: this analysis will lay the foundation for the study of the corresponding optimal control problem. Concerning the optimization problem, we address the existence of minimizers and establish both first-order necessary and second-order sufficient conditions for optimality. The mathematically challenging second-order analysis is completely performed here, after showing that the solution mapping is twice continuously differentiable between suitable Banach spaces via the implicit function theorem. Then, we completely identify the second-order Fréchet derivative of the control-to-state operator and carry out a thorough and detailed investigation about the related properties.
- ItemOptimal velocity control of a viscous Cahn-Hilliard system with convection and dynamic boundary conditions(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2017) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenIn this paper, we investigate a distributed optimal control problem for a convective viscous CahnHilliard system with dynamic boundary conditions. Such systems govern phase separation processes between two phases taking place in an incompressible fluid in a container and, at the same time, on the container boundary. The cost functional is of standard tracking type, while the control is exerted by the velocity of the fluid in the bulk. In this way, the coupling between the state (given by the associated order parameter and chemical potential) and control variables in the governing system of nonlinear partial differential equations is bilinear, which presents an additional difficulty for the analysis. The nonlinearities in the bulk and surface free energies are of logarithmic type, which entails that the thermodynamic forces driving the phase separation process may become singular. We show existence for the optimal control problem under investigation, prove the Fréchet differentiability of the associated control-to-state mapping in suitable Banach spaces, and derive the first-order necessary optimality conditions in terms of a variational inequality and the associated adjoint system. Due to the strong nonlinear couplings between state variables and control, the corresponding proofs require a considerable analytical effort.
- ItemSparse optimal control of a phase field system with singular potentials arising in the modeling of tumor growth(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2020) Sprekels, Jürgen; Tröltzsch, FrediIn this paper, we study an optimal control problem for a nonlinear system of reaction-diffusion equations that constitutes a simplified and relaxed version of a thermodynamically consistent phase field model for tumor growth originally introduced in [13]. The model takes the effect of chemotaxis into account but neglects velocity contributions. The unknown quantities of the governing state equations are the chemical potential, the (normalized) tumor fraction, and the nutrient extra-cellular water concentration. The equation governing the evolution of the tumor fraction is dominated by the variational derivative of a double-well potential which may be of singular (e.g., logarithmic) type. In contrast to the recent paper [10] on the same system, we consider in this paper sparsity effects, which means that the cost functional contains a nondifferentiable (but convex) contribution like the L1-norm. For such problems, we derive first-order necessary optimality conditions and conditions for directional sparsity, both with respect to space and time, where the latter case is of particular interest for practical medical applications in which the control variables are given by the administration of cytotoxic drugs or by the supply of nutrients. In addition to these results, we prove that the corresponding control-to-state operator is twice continuously differentiable between suitable Banach spaces, using the implicit function theorem. This result, which complements and sharpens a differentiability result derived in [10], constitutes a prerequisite for a future derivation of second-order sufficient optimality conditions.
- ItemOptimal velocity control of a convective Cahn-Hilliard system with double obstacles and dynamic boundary conditions: A deep quench approach(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2017) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenIn this paper, we investigate a distributed optimal control problem for a convective viscous CahnHilliard system with dynamic boundary conditions. Such systems govern phase separation processes between two phases taking place in an incompressible fluid in a container and, at the same time, on the container boundary. The cost functional is of standard tracking type, while the control is exerted by the velocity of the fluid in the bulk. In this way, the coupling between the state (given by the associated order parameter and chemical potential) and control variables in the governing system of nonlinear partial differential equations is bilinear, which presents a difficulty for the analysis. In contrast to the previous paper Optimal velocity control of a viscous CahnHilliard system with convection and dynamic boundary conditions by the same authors, the bulk and surface free energies are of double obstacle type, which renders the state constraint nondifferentiable. It is well known that for such cases standard constraint qualifications are not satisfied so that standard methods do not apply to yield the existence of Lagrange multipliers. In this paper, we overcome this difficulty by taking advantage of results established in the quoted paper for logarithmic nonlinearities, using a so-called deep quench approximation. We derive results concerning the existence of optimal controls and the first-order necessary optimality conditions in terms of a variational inequality and the associated adjoint system.
- ItemOptimal control of an Allen-Cahn equation with singular potentials and dynamic boundary condition(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2012) Colli, Pierluigi; Sprekels, JürgenIn this paper, we investigate optimal control problems for AllenCahn equations with singular nonlinearities and a dynamic boundary condition involving singular nonlinearities and the Laplace Beltrami operator. The approach covers both the cases of distributed controls and of boundary controls. The cost functional is of standard tracking type, and box constraints for the controls are prescribed. Parabolic problems with nonlinear dynamic boundary conditions involving the LaplaceBeltrami operation have recently drawn increasing attention due to their importance in applications, while their optimal control was apparently never studied before. In this paper, we first extend known well-posedness and regularity results for the state equation and then show the existence of optimal controls and that the control-to-state mapping is twice continuously Fréchet differentiable between appropriate function spaces. Based on these results, we establish the firstorder necessary optimality conditions in terms of a variational inequality and the adjoint state equation, and we prove second-order sufficient optimality conditions
- ItemA boundary control problem for the viscous Cahn-Hilliard equation with dynamic boundary conditions(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenA boundary control problem for the viscous Cahn-Hilliard equations with possibly singular potentials and dynamic boundary conditions is studied and first order necessary conditions for optimality are proved.
- ItemOptimal control problems with sparsity for phase field tumor growth models involving variational inequalities(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2021) Colli, Pierluigi; Signori, Andrea; Sprekels, JürgenThis paper treats a distributed optimal control problem for a tumor growth model of Cahn--Hilliard type including chemotaxis. The evolution of the tumor fraction is governed by a variational inequality corresponding to a double obstacle nonlinearity occurring in the associated potential. In addition, the control and state variables are nonlinearly coupled and, furthermore, the cost functional contains a nondifferentiable term like the $L^1$--norm in order to include sparsity effects which is of utmost relevance, especially time sparsity, in the context of cancer therapies as applying a control to the system reflects in exposing the patient to an intensive medical treatment. To cope with the difficulties originating from the variational inequality in the state system, we employ the so-called ``deep quench approximation'' in which the convex part of the double obstacle potential is approximated by logarithmic functions. For such functions, first-order necessary conditions of optimality can be established by invoking recent results. We use these results to derive corresponding optimality conditions also for the double obstacle case, by deducing a variational inequality in terms of the associated adjoint state variables. The resulting variational inequality can be exploited to also obtain sparsity results for the optimal controls.
- ItemOptimal boundary control of a viscous Cahn-Hilliard system with dynamic boundary condition and double obstacle potentials(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Colli, Pierluigi; Farshbaf Shaker, Mohammad Hassan; Gilardi, Gianni; Sprekels, JürgenIn this paper, we investigate optimal boundary control problems for Cahn--Hilliard variational inequalities with a dynamic boundary condition involving double obstacle potentials and the Laplace--Beltrami operator. The cost functional is of standard tracking type, and box constraints for the controls are prescribed. We prove existence of optimal controls and derive first-order necessary conditions of optimality. The general strategy, which follows the lines of the recent approach by Colli, Farshbaf-Shaker, Sprekels (see Appl. Math. Optim., 2014) to the (simpler) Allen--Cahn case, is the following: we use the results that were recently established by Colli, Gilardi, Sprekels in the preprint arXiv:1407.3916 [math.AP] for the case of (differentiable) logarithmic potentials and perform a so-called ``deep quench limit''. Using compactness and monotonicity arguments, it is shown that this strategy leads to the desired first-order necessary optimality conditions for the case of (non-differentiable) double obstacle potentials.