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- ItemA boundary control problem for the pure Cahn-Hilliard equation with dynamic boundary conditions(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2015) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenA boundary control problem for the pure Cahn-Hilliard equations with possibly singular potentials and dynamic boundary conditions is studied and first-order necessary conditions for optimality are proved.
- ItemSecond-order analysis of an optimal control problem in a phase field tumor growth model with singular potentials and chemotaxis(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2020) Colli, Pierluigi; Signori, Andrea; Sprekels, JürgenThis paper concerns a distributed optimal control problem for a tumor growth model of Cahn--Hilliard type including chemotaxis with possibly singular anpotentials, where the control and state variables are nonlinearly coupled. First, we discuss the weak well-posedness of the system under very general assumptions for the potentials, which may be singular and nonsmooth. Then, we establish the strong well-posedness of the system in a reduced setting, which however admits the logarithmic potential: this analysis will lay the foundation for the study of the corresponding optimal control problem. Concerning the optimization problem, we address the existence of minimizers and establish both first-order necessary and second-order sufficient conditions for optimality. The mathematically challenging second-order analysis is completely performed here, after showing that the solution mapping is twice continuously differentiable between suitable Banach spaces via the implicit function theorem. Then, we completely identify the second-order Fréchet derivative of the control-to-state operator and carry out a thorough and detailed investigation about the related properties.
- ItemSparse optimal control of a phase field system with singular potentials arising in the modeling of tumor growth(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2020) Sprekels, Jürgen; Tröltzsch, FrediIn this paper, we study an optimal control problem for a nonlinear system of reaction-diffusion equations that constitutes a simplified and relaxed version of a thermodynamically consistent phase field model for tumor growth originally introduced in [13]. The model takes the effect of chemotaxis into account but neglects velocity contributions. The unknown quantities of the governing state equations are the chemical potential, the (normalized) tumor fraction, and the nutrient extra-cellular water concentration. The equation governing the evolution of the tumor fraction is dominated by the variational derivative of a double-well potential which may be of singular (e.g., logarithmic) type. In contrast to the recent paper [10] on the same system, we consider in this paper sparsity effects, which means that the cost functional contains a nondifferentiable (but convex) contribution like the L1-norm. For such problems, we derive first-order necessary optimality conditions and conditions for directional sparsity, both with respect to space and time, where the latter case is of particular interest for practical medical applications in which the control variables are given by the administration of cytotoxic drugs or by the supply of nutrients. In addition to these results, we prove that the corresponding control-to-state operator is twice continuously differentiable between suitable Banach spaces, using the implicit function theorem. This result, which complements and sharpens a differentiability result derived in [10], constitutes a prerequisite for a future derivation of second-order sufficient optimality conditions.
- ItemA boundary control problem for the viscous Cahn-Hilliard equation with dynamic boundary conditions(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenA boundary control problem for the viscous Cahn-Hilliard equations with possibly singular potentials and dynamic boundary conditions is studied and first order necessary conditions for optimality are proved.
- ItemSecond-order analysis of a boundary control problem for the viscous Cahn-Hilliard equation with dynamic boundary condition(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Colli, Pierluigi; Farshbaf Shaker, Mohammad Hassan; Gilardi, Gianni; Sprekels, JürgenIn this paper we establish second-order sufficient optimality conditions for a boundary control problem that has been introduced and studied by three of the authors in the preprint arXiv:1407.3916. This control problem regards the viscous Cahn-Hilliard equation with possibly singular potentials and dynamic boundary conditions.
- ItemOn an application of Tikhonovs fixed point theorem to a nonlocal Cahn-Hilliard type system modeling phase separation(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2015) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenThis paper investigates a nonlocal version of a model for phase separation on an atomic lattice that was introduced by P. Podio-Guidugli in Ric. Mat. 55 (2006) 105-118. The model consists of an initial-boundary value problem for a nonlinearly coupled system of two partial differential equations governing the evolution of an order parameter p and the chemical potential my. Singular contributions to the local free energy in the form of logarithmic or ouble-obstacle potentials are admitted. In contrast to the local model, which was studied by P. Podio-Guidugli and the present authors in a series of recent publications, in the nonlocal case the equation governing the evolution of the order parameter contains in place of the Laplacian a nonlocal expression that originates from nonlocal contributions to the free energy and accounts for possible long-range interactions between the atoms. It is shown that just as in the local case the model equations are well posed, where the technique of proving existence is entirely different: it is based on an application of Tikhonovs fixed point theorem in a rather unusual separable and reflexive Banach space.
- ItemA boundary control problem for the pure Cahn–Hilliard equation with dynamic boundary conditions(Berlin ; Boston, Mass. : de Gruyter, 2015) Colli, Pierluigi; Gilardi, Gianni; Sprekels, JürgenA boundary control problem for the pure Cahn–Hilliard equations with possibly singular potentialsand dynamic boundary conditions is studied and rst-order necessary conditions for optimality are proved.