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Now showing 1 - 4 of 4
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    Interaction Network Analysis Using Semantic Similarity Based on Translation Embeddings
    (Berlin ; Heidelberg : Springer, 2019) Manzoor Bajwa, Awais; Collarana, Diego; Vidal, Maria-Esther; Acosta, Maribel; Cudré-Mauroux, Philippe; Maleshkova, Maria; Pellegrini, Tassilo; Sack, Harald; Sure-Vetter, York
    Biomedical knowledge graphs such as STITCH, SIDER, and Drugbank provide the basis for the discovery of associations between biomedical entities, e.g., interactions between drugs and targets. Link prediction is a paramount task and represents a building block for supporting knowledge discovery. Although several approaches have been proposed for effectively predicting links, the role of semantics has not been studied in depth. In this work, we tackle the problem of discovering interactions between drugs and targets, and propose SimTransE, a machine learning-based approach that solves this problem effectively. SimTransE relies on translating embeddings to model drug-target interactions and values of similarity across them. Grounded on the vectorial representation of drug-target interactions, SimTransE is able to discover novel drug-target interactions. We empirically study SimTransE using state-of-the-art benchmarks and approaches. Experimental results suggest that SimTransE is competitive with the state of the art, representing, thus, an effective alternative for knowledge discovery in the biomedical domain.
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    Formalizing Gremlin pattern matching traversals in an integrated graph Algebra
    (Aachen, Germany : RWTH Aachen, 2019) Thakkar, Harsh; Auer, Sören; Vidal, Maria-Esther; Samavi, Reza; Consens, Mariano P.; Khatchadourian, Shahan; Nguyen, Vinh; Sheth, Amit; Giménez-García, José M.; Thakkar, Harsh
    Graph data management (also called NoSQL) has revealed beneficial characteristics in terms of flexibility and scalability by differ-ently balancing between query expressivity and schema flexibility. This peculiar advantage has resulted into an unforeseen race of developing new task-specific graph systems, query languages and data models, such as property graphs, key-value, wide column, resource description framework (RDF), etc. Present-day graph query languages are focused towards flex-ible graph pattern matching (aka sub-graph matching), whereas graph computing frameworks aim towards providing fast parallel (distributed) execution of instructions. The consequence of this rapid growth in the variety of graph-based data management systems has resulted in a lack of standardization. Gremlin, a graph traversal language, and machine provide a common platform for supporting any graph computing sys-tem (such as an OLTP graph database or OLAP graph processors). In this extended report, we present a formalization of graph pattern match-ing for Gremlin queries. We also study, discuss and consolidate various existing graph algebra operators into an integrated graph algebra.
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    Why reinvent the wheel: Let's build question answering systems together
    (New York City : Association for Computing Machinery, 2018) Singh, K.; Radhakrishna, A.S.; Both, A.; Shekarpour, S.; Lytra, I.; Usbeck, R.; Vyas, A.; Khikmatullaev, A.; Punjani, D.; Lange, C.; Vidal, Maria-Esther; Lehmann, J.; Auer, Sören
    Modern question answering (QA) systems need to flexibly integrate a number of components specialised to fulfil specific tasks in a QA pipeline. Key QA tasks include Named Entity Recognition and Disambiguation, Relation Extraction, and Query Building. Since a number of different software components exist that implement different strategies for each of these tasks, it is a major challenge to select and combine the most suitable components into a QA system, given the characteristics of a question. We study this optimisation problem and train classifiers, which take features of a question as input and have the goal of optimising the selection of QA components based on those features. We then devise a greedy algorithm to identify the pipelines that include the suitable components and can effectively answer the given question. We implement this model within Frankenstein, a QA framework able to select QA components and compose QA pipelines. We evaluate the effectiveness of the pipelines generated by Frankenstein using the QALD and LC-QuAD benchmarks. These results not only suggest that Frankenstein precisely solves the QA optimisation problem but also enables the automatic composition of optimised QA pipelines, which outperform the static Baseline QA pipeline. Thanks to this flexible and fully automated pipeline generation process, new QA components can be easily included in Frankenstein, thus improving the performance of the generated pipelines.
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    Preface
    (Aachen, Germany : RWTH Aachen, 2019) Kaffee, Lucie-Aimee; Endris, Kemele M.; Vidal, Maria-Esther; Comerio, Marco; Sadeghi, Mersedeh; Chaves-Fraga; David, Colpaert Pieter; Kaffee, Lucie Aimée; Endris, Kemele M.; Vidal, María-Esther; Comerio, Marco; Sadeghi, Mersedeh; Chaves-Fraga, David; Colpaert, Pieter
    This volumne presents the proceedings of the 1st International Workshop on Approaches for Making Data Interoperable (AMAR 2019) and 1st International Workshop on Semantics for Transport (Sem4Tra) held in Karlsruhe, Germany, September 9, 2019, co-located with SEMANTiCS 2019. Interoperability of data is an important factor to make transportation data accessible, therefore we present the topics alongside each other in this proceedings.