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- ItemThe Exploration of Aroyltrimethylgermane as Potent Synthetic Origins and Their Preparation(Amsterdam [u.a.] : Elsevier, 2019) Yuan, Yang; Zhang, Youcan; Chen, Bo; Wu, Xiao-FengThe synthetic utilities of acylgermanes are surprisingly rarely explored compared with their analogues. In this communication, the survey of aroyltrimethylgermane as potent synthetic origins has been studied. A variety of novel chemical transformations have been realized, including using the acylgermane group as a directing group in Rh-catalyzed aromatic C-H alkenylation reaction and Ir-catalyzed aromatic C-H amidation reactions. Additionally, a general approach for acylgermanes preparation has been established as well. The catalytic system proceeds effectively in the presence of Pd(OAc)2/BINOL-based monophosphite (L11) and allows for the straightforward access to a wide range of functionalized acylgermanes in high yields. © 2019 The Author(s)Catalysis; Organic Synthesis; Organic Reaction; Chemical Synthesis © 2019 The Author(s)
- ItemCu/Pd-catalyzed borocarbonylative trifunctionalization of alkynes and allenes: synthesis of β-geminal-diboryl ketones(Beijing : Science China Press, 2021) Yuan, Yang; Wu, Fu-Peng; Spannenberg, Anke; Wu, Xiao-FengFunctionalized bisboryl compounds have recently emerged as a new class of synthetically useful building blocks in organic synthesis. Herein, we report an efficient strategy to synthesize β-geminal-diboryl ketones enabled by a Cu/Pd-catalyzed borocarbonylative trifunctionalization of readily available alkynes and allenes. This reaction promises to be a useful method for the synthesis of functionalized β-geminal-diboryl ketones with broad functional group tolerance. Mechanistic studies suggest that the reaction proceeds through borocarbonylation/hydroboration cascade of both alkynes and allenes.