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Now showing 1 - 10 of 299
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    Toward mixed-element meshing based on restricted Voronoi diagrams
    (Amsterdam [u.a.] : Elsevier, 2014) Pellerin, J.; Lévy, B.; Caumon, G.
    In this paper we propose a method to generate mixed-element meshes (tetrahedra, triangular prisms, square pyramids) for B-Rep models. The vertices, edges, facets, and cells of the final volumetric mesh are determined from the combinatorial analysis of the intersections between the model components and the Voronoi diagram of sites distributed to sample the model. Inside the volumetric regions, Delaunay tetrahedra dual of the Voronoi diagram are built. Where the intersections of the Voronoi cells with the model surfaces have a unique connected component, tetrahedra are modified to fit the input triangulated surfaces. Where these intersections are more complicated, a correspondence between the elements of the Voronoi diagram and the elements of the mixedelement mesh is used to build the final volumetric mesh. The method which was motivated by meshing challenges encountered in geological modeling is demonstrated on several 3D synthetic models of subsurface rock volumes.
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    Effective Numerical Algorithm for Simulations of Beam Stabilization in Broad Area Semiconductor Lasers and Amplifiers
    (Milton Park : Taylor and Francis Ltd., 2014) Radziunas, M.; Čiegis, R.
    Abstract: A 2 + 1 dimensional PDE traveling wave model describing spatial-lateral dynamics of edge-emitting broad area semiconductor devices is considered. A numerical scheme based on a split-step Fourier method is presented. The domain decomposition method is used to parallelize the sequential algorithm. The parallel algorithm is implemented by using Message Passing Interface system, results of computational experiments are presented and the scalability of the algorithm is analyzed. Simulations of the model equations are used for optimizing of existing devices with respect to the emitted beam quality, as well as for creating and testing of novel device design concepts.
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    Well-being in amyotrophic lateral sclerosis: A pilot experience sampling study
    (Lausanne : Frontiers Research Foundation, 2014) Real, R.G.; Dickhaus, T.; Ludolph, A.; Hautzinger, M.; Kübler, A.
    Objective: The aim of this longitudinal study was to identify predictors of instantaneous well-being in patients with amyotrophic lateral sclerosis (ALS). Based on flow theory well-being was expected to be highest when perceived demands and perceived control were in balance, and that thinking about the past would be a risk factor for rumination which would in turn reduce well-being. Methods: Using the experience sampling method, data on current activities, associated aspects of perceived demands, control, and well-being were collected from 10 patients with ALS three times a day for two weeks. Results: Results show that perceived control was uniformly and positively associated with well-being, but that demands were only positively associated with well-being when they were perceived as controllable. Mediation analysis confirmed thinking about the past, but not thinking about the future, to be a risk factor for rumination and reduced well-being. Discussion: Findings extend our knowledge of factors contributing to well-being in ALS as not only perceived control but also perceived demands can contribute to well-being. They further show that a focus on present experiences might contribute to increased well-being.
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    Insulin adsorption to catheter materials used for intensive insulin therapy in critically ill patients: Polyethylene versus polyurethane - possible cause of variation in glucose control?
    (Sharjah : Bentham Science Publishers B.V., 2014) Ley, S.C.; Ammann, J.; Herder, C.; Dickhaus, T.; Hartmann, M.; Kindgen-Milles, D.
    Introduction: Restoring and maintaining normoglycemia by intensified insulin therapy in critically ill patients is a matter of ongoing debate since the risk of hypoglycemia may outweigh positive effects on morbidity and mortality. In this context, adsorption of insulin to different catheter materials may contribute to instability of glucose control. We studied the adsorption of insulin to different tubing materials in vitro and the effects on glycemic control in vivo. Materials and Methods: In vitro experiments: A syringe pump was filled with 50 IU insulin diluted to 50 ml saline. A flow of 2 ml/h was perfused through polyethylene (PET) or polyurethane (PUR) tubing. Insulin concentrations were measured at the end of the tube for 24 hours using Bradford's protein assay. In vivo study: In a randomized double-blinded cross-over design, 10 intensive care patients received insulin via PET and PUR tubes for 24 hours each, targeting blood glucose levels of 80-150 mg/dl. We measured blood glucose levels, the insulin dose required to maintain target levels, and serum insulin and C-peptide levels. Results: In vitro experiments: After the start of the insulin infusion, only 20% (median, IQR 20-27) (PET) and 22% (IQR 16-27) (PUR) of the prepared insulin concentration were measured at the end of the 2 meter tubing. Using PET, after one hour infusion the concentration increased to 34% (IQR 29-36) and did not increase significantly during the next 24 hours (39% (IQR 39-40)). Using PUR, higher concentrations were detected than for PET at every measurement from 1 hour (82% (IQR 70-86)) to 24 hours (79% (IQR 64-87)). In vivo study: Glycemic control was effective and not different between groups. Significantly higher volumes of insulin solution had to be infused with PET compared to PUR (median PET 70.0 (IQR 56-82) ml vs. PUR 42 (IQR 31-63) ml; p=0.0015). Serum insulin concentrations did not decrease significantly one hour after changing to PET or PUR tubing. Conclusion: Polyurethane tubing systems allow application of insulin with significantly lower adsorption rates than polyethylene tubing systems. As a consequence, less insulin solution has to be infused to patients for effective blood glucose control. Tubing material of the insulin infusion may be crucial for safe and effective glycemic control in critically ill patients.
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    Modeling and simulations of beam stabilization in edge-emitting broad area semiconductor devices
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2013) Radziunas, Mindaugas; Cˇ iegis, Raimondas
    A 2+1 dimensional PDE traveling wave model describing spatial-lateral dynamics of edge-emitting broad area semiconductor devices is considered. A numerical scheme based on a split-step Fourier method is presented and implemented on a parallel compute cluster. Simulations of the model equations are used for optimizing of existing devices with respect to the emitted beam quality, as well as for creating and testing of novel device design concepts
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    Bistability and hysteresis in an optically injected two-section semiconductor laser
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Pimenov, Alexander; Viktorov, Evgeniy A.; Hegarty, Stephen P.; Habruseva, Tatiana; Huyet, Guillaume; Rachinskii, Dmitrii; Vladimirov, Andrei G.
    The effect of coherent single frequency injection on two-section semiconductor lasers is studied numerically using a model based on a set of delay differential equations. The existence of bistability between different CW and non-stationary regimes of operation is demonstrated in the case of sufficiently large linewidth enhancement factors.
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    On multivariate chi-square distributions and their applications in testing multiple hypotheses
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Dickhaus, Thorsten; Royen, Thomas
    We are considered with three different types of multivariate chi-square distributions. Their members play important roles as limiting distributions of vectors of test statistics in several applications of multiple hypotheses testing. We explain these applications and provide formulas for computing multiplicity-adjusted p-values under the respective global hypothesis.
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    Optimal control of elastic vector-valued AllenCahn variational inequalities
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2013) Farshbaf-Shaker, Mohammad Hassan; Hecht, Claudia
    In this paper we consider a elastic vector-valued AllenCahn MPCC (Mathematical Programs with Complementarity Constraints) problem. We use a regularization approach to get the optimality system for the subproblems. By passing to the limit in the optimality conditions for the regularized subproblems, we derive certain generalized first-order necessary optimality conditions for the original problem.
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    Equilibrium shapes of poly-crystalline silicon nanodots
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2013) Korzec, Maciek D.; Roczen, Maurizio; Schade, Martin; Wagner, Barbara; Rech, Bernd
    This study is concerned with the topography of nanostructures consisting of arrays of poly-crystalline nanodots. Guided by transmission electron microscopy (TEM) measurements of crystalline Si (c-Si) nanodots that evolved from a dewetting process of an amorphous Si (a-Si) layer from a SiO2 coated substrate, we investigate appropriate formulations for the surface energy density and transitions of energy density states at grain boundaries. We introduce a new numerical minimization formulation that allows to account for adhesion energy from an underlying substrate. We demonstrate our approach first for the free standing case, where the solutions can be compared to well-known Wulff constructions, before we treat the general case for interfacial energy settings that support partial wetting. We then use our method to predict the morphologies of poly-crystalline silicon nanodots.
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    Femtosecond filamentation by intensity clamping at a Freeman resonance
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2014) Hofmann, Michael; Brée, Carsten
    [no abstract available]