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End date: 2024 × Start date: 2022 × End date: 2024 × Start date: 2020 × Type: Article × Version: updatedVersion ×

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    A general strategy for the synthesis of α-trifluoromethyl- and α-perfluoroalkyl-β-lactams via palladium-catalyzed carbonylation
    (Cambridge : RSC, 2021) Li, Yang; Zhang, Cai-Lin; Huang, Wei-Heng; Sun, Ning; Hao, Meng; Neumann, Helfried; Beller, Matthias
    β-Lactam compounds play a key role in medicinal chemistry, specifically as the most important class of antibiotics. Here, we report a novel one-step approach for the synthesis of α-(trifluoromethyl)-β-lactams and related products from fluorinated olefins, anilines and CO. Utilization of an advanced palladium catalyst system with the Ruphos ligand allows for selective cycloaminocarbonylations to give diverse fluorinated β-lactams in high yields. © The Royal Society of Chemistry 2021.
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    Das Freiburger Magisterdiplom für den Pharmazeuten Johann Christoph Friedrich Weissmann (revidierte und vermehrte Fassung)
    (Tübingen : Universitätsbibliothek Tübingen, 2023) Diebold, Steffen M.
    Bei dem hier wiedergegebenen Diplom für einen Apotheker handelt es sich um eine handschriftliche Urkunde vom 16. Juni 1803 aus Freiburg im Breisgau, der damals bedeutendsten Stadt in Vorderösterreich. Der pharmaziehistorisch interessante Schriftsatz bietet ein Beispiel universitären Verwaltungshandelns zum Ende des Alten Reichs, des Heiligen Römischen Reichs Deutscher Nation (Sacrum Imperium Romanum Nationis Germaniae). Auf eine kurze Beschreibung der lateinischen Urkunde (Diplomatik) folgt eine (textnahe Gebrauchs-) Übersetzung durch den Autor.
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    Corona - Wahn oder Wissenschaft? (Plädoyer für Vernunft)
    (Nürnberg : Gesellschaft für Kritische Philosophie GKP, 2022-10) Diebold, Steffen M.
    The corona pandemic poses major challenges for society. Many people lack (basic) scientific knowledge. They are skeptical and distrust research principles and concepts. Esotericism and (super) belief replace their access to reality. Not only facts are recently "alternative". Pseudo-scientific healing methods and occult procedures have long been presented to the public as equivalent alternatives to modern medicine, despite the lack of evidence of their effectiveness. Just as if reason or nonsense were just a question of personal taste, a different world view. Seconded by talk of an "exaggeratedly scientific world view", empiricism and logic were systematically defamed. As a result of this distorted picture, all kinds of conspiracy theories are now rampant. Spiritual healers, seers, shamans, charlatans, quacks, sectarians, and zealots of all stripes and persuasions are in demand. A diffuse pandemic management and miserable communication do the rest and contribute to the fact that infection control measures are often flatly rejected and vaccination rates can hardly be increased significantly.