2014, Hohlfeld, Michael, Tobschall, Esther

Der Beitrag beschreibt zunächst den Ist-Zustand des Zusammenspiels der von der TIB betriebenen Virtuellen Fachbibliotheken sowie dem Fachportal GetInfo. Er gibt einen Ausblick auf ein neues übergreifendes Webportal der TIB, in welchem GetInfo aufgehen wird und welches künftige Fachinformationsdienste der TIB in Form von erweiterten Facheinstiegen anbieten wird – unter Einbindung neuartiger Dienste für Fachcommunities sowie Fachausschnitten der medienspezifischen Portale der TIB.

2019, Frosch, Timea, Knebl, Andreas, Frosch, Torsten

Innovations in Raman spectroscopic techniques provide a potential solution to current problems in pharmaceutical drug monitoring. This review aims to summarize the recent advances in the field. The developments of novel plasmonic nanoparticles continuously push the limits of Raman spectroscopic detection. In surface-enhanced Raman spectroscopy (SERS), these particles are used for the strong local enhancement of Raman signals from pharmaceutical drugs. SERS is increasingly applied for forensic trace detection and for therapeutic drug monitoring. In combination with spatially offset Raman spectroscopy, further application fields could be addressed, e.g. in situ pharmaceutical quality testing through the packaging. Raman optical activity, which enables the thorough analysis of specific chiral properties of drugs, can also be combined with SERS for signal enhancement. Besides SERS, micro- and nano-structured optical hollow fibers enable a versatile approach for Raman signal enhancement of pharmaceuticals. Within the fiber, the volume of interaction between drug molecules and laser light is increased compared with conventional methods. Advances in fiber-enhanced Raman spectroscopy point at the high potential for continuous online drug monitoring in clinical therapeutic diagnosis. Furthermore, fiber-array based non-invasive Raman spectroscopic chemical imaging of tablets might find application in the detection of substandard and counterfeit drugs. The discussed techniques are promising and might soon find widespread application for the detection and monitoring of drugs in various fields.

2013, Mensing, Petra

Das Hauptziel des EU-Projektes Linked Heritage1 war die Einspielung von 3 Millionen neuen Datensätzen in die Europeana. Die 38 Projektpartner kamen aus 20 europäischen Ländern plus Israel und Russland. Die Technische Informationsbibliothek (TIB) Hannover stellte für dieses Projekt Metadaten aus dem Kompetenzzentrum für nichttextuelle Materialen sowie aus dem Bereich Forschungsdaten bereit und war an drei der sieben Arbeitspakete2 beteiligt.

2013, Mostafaiyan, M., Saeb, M.R., Ahmadi, Z., Khonakdar, H.A., Wagenknecht, U., Heinrich, G.

In this work, the dynamic deformation of a viscose Newtonian droplet passing through cylindrical converging dies has been studied. The changes in the interfacial area between two immiscible Newtonian fluids have been considered as a variable representing the time-dependent deformation of a circular droplet along converging dies. To do so, a surface tracking method has been incorporated into a finite element code, developed by the authors, which quantifies the deformation of the droplet through the converging path, and where the surface area of the deformed drop has been consequently chosen as a criterion for a two-phase interface. In this study, it has been revealed that by changing both rheological and geometrical parameters it is possible to manage the value of interface area between two phases. Ultimately, a unique curve is developed for each droplet to primary phase viscosity ratio which can correlate drop deformation with geometrical parameters.