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- ItemBiobank Oversight and Sanctions Under the General Data Protection Regulation(Dordrecht ; Heidelberg ; New York ; London : Springer, 2021) Hallinan, Dara; Slokenberga, Santa; Tzortzatou, Olga; Reichel, JaneThis contribution offers an insight into the function and problems of the oversight and sanctions mechanisms outlined in the General Data Protection Regulation as they relate to the biobanking context. These mechanisms might be considered as meta-mechanisms—mechanisms relating to, but not consisting of, substantive legal principles—functioning in tandem to ensure biobank compliance with data protection principles. Each of the mechanisms outlines, on paper at least, comprehensive and impressive compliance architecture—both expanding on their capacity in relation to Directive 95/46. Accordingly, each mechanism looks likely to have a significant and lasting impact on biobanks and biobanking. Despite this comprehensiveness, however, the mechanisms are not immune from critique. Problems appear regarding the standard of protection provided for research subject rights, regarding the disproportionate impact on legitimate interests tied up with the biobanking process—particularly genomic research interests—and regarding their practical implementability in biobanking.
- Item24th International Conference on Business Information Systems : Preface(Hannover : TIB Open Publishing, 2021) Abramowicz, Witold; Auer, Sören; Abramowicz, Witold; Auer, Sören; Lewańska, Elżbieta
- ItemReadiness for Innovation of Emerging Grass-Based Businesses(Basel : MDPI, 2022) Orozco, Richard; Grundmann, PhilippNew business opportunities based on grassland and green fodder present a promising avenue to realize the transition towards a circular and sustainable bio-based economy. Yet, such potential remains largely untapped and grass-based products and businesses remain a small niche in the global economy. To understand this phenomenon, this paper introduces and operationalizes a model to assess innovation readiness built around seven focus areas: technology, manufacturing, business, IPR, customer, team, and funding readiness with their own detailed “progress scales.” We employ necessary condition analysis (NCA) to identify limiting factors and bottlenecks in actual business situations. Our results reveal that lack of consumer awareness, infant conversion technologies and paucity of long-term investments that support emerging bio-based businesses are the most limiting conditions for the growth of emerging grass-based markets. The present study advances our understanding of the factors that limit complex innovations in grassland systems. Focusing on necessary conditions in a coordinated way between practitioners and policy makers by giving priority to fostering positive awareness of bioeconomy businesses, developing conversion technologies, and improving access to capital is a recommended approach to foster emerging grass-based innovations.
- ItemInfluence of the Reaction Injection Moulding Process on the Thermomechanical Behaviour of Fast Curing Polyurethane(Basel : MDPI, 2022) Lehmenkühler, Peter; Stommel, MarkusIn this contribution, the influence of the reaction injection moulding process on the thermomechanical material behaviour of aliphatic hexamethylene diisocyanate (HDI) based fast curing polyurethane is demonstrated. Uniaxial tensile tests, temperature-frequency dependent dynamic mechanical thermal analysis (DMTA) and Differential Scanning Calorimetry (DSC) are used to show the differences in properties for ten different sets of process parameters. The mould and resin components temperature, the mass flow during the filling process and the residence time during the reaction process of the polyurethane are varied in several stages. Further experiments to determine the molar mass of the molecular chain between two crosslinking points of the polyurethane are used to explain the process influences on the thermomechanical properties. Thus, a direct correlation between manufacturing and material properties is shown. In addition, the mutual effect of the different parameters and their overall influence on the material behaviour is presented.
- ItemLandscape matters: Insights from the impact of mega-droughts on Colombia's energy transition(Amsterdam [u.a.] : Elsevier, 2020) Weng, Wei; Becker, Stefanie L.; Lüdeke, Matthias K. B.; Lakes, TobiaMega-droughts can cause disruption to the affected society sparking a transition. We explore the causes and effects of the 2015−2016 mega-drought in Colombia. Using the multi-level perspective as a framework, we found that the mega-drought sparked an energy transition in Colombia whose dynamics were impacted both by the institutionalization of niches as well as the ability to predict the next drought. We were able to trace, using the current understanding of anthropogenic forces, the cause of the mega-drought to socio-technical landscape development influenced by human-induced warming and land use change. We found that the regimes in Bolivia and Brazil were able to influence the landscape through deforestation, and hence contribute to the intensity of a mega-drought in Colombia. The knowledge that a regime can cause disruption in regimes in other geographies and sectors has implications for transition research as well as decision-making for coping with droughts and other disasters. © 2020
- ItemShort-dated smile under rough volatility: asymptotics and numerics(London : Taylor & Francis, 2021) Friz, Peter K.; Gassiat, Paul; Pigato, PaoloIn Friz et al. [Precise asymptotics for robust stochastic volatility models. Ann. Appl. Probab, 2021, 31(2), 896–940], we introduce a new methodology to analyze large classes of (classical and rough) stochastic volatility models, with special regard to short-time and small-noise formulae for option prices, using the framework [Bayer et al., A regularity structure for rough volatility. Math. Finance, 2020, 30(3), 782–832]. We investigate here the fine structure of this expansion in large deviations and moderate deviations regimes, together with consequences for implied volatility. We discuss computational aspects relevant for the practical application of these formulas. We specialize such expansions to prototypical rough volatility examples and discuss numerical evidence.