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    Optimality Conditions and Moreau-Yosida Regularization for Almost Sure State Constraints
    (Paris : EDP Sciences, 2022) Geiersbach, Caroline; Hintermüller, Michael
    We analyze a potentially risk-averse convex stochastic optimization problem, where the control is deterministic and the state is a Banach-valued essentially bounded random variable. We obtain strong forms of necessary and sufficient optimality conditions for problems subject to equality and conical constraints. We propose a Moreau-Yosida regularization for the conical constraint and show consistency of the optimality conditions for the regularized problem as the regularization parameter is taken to infinity.
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    Second-order analysis of an optimal control problem in a phase field tumor growth model with singular potentials and chemotaxis
    (Les Ulis : EDP Sciences, 2021) Colli, Pierluigi; Signori, Andrea; Sprekels, Jürgen
    This paper concerns a distributed optimal control problem for a tumor growth model of Cahn–Hilliard type including chemotaxis with possibly singular potentials, where the control and state variables are nonlinearly coupled. First, we discuss the weak well-posedness of the system under very general assumptions for the potentials, which may be singular and nonsmooth. Then, we establish the strong well-posedness of the system in a reduced setting, which however admits the logarithmic potential: this analysis will lay the foundation for the study of the corresponding optimal control problem. Concerning the optimization problem, we address the existence of minimizers and establish both first-order necessary and second-order sufficient conditions for optimality. The mathematically challenging second-order analysis is completely performed here, after showing that the solution mapping is twice continuously differentiable between suitable Banach spaces via the implicit function theorem. Then, we completely identify the second-order Fréchet derivative of the control-to-state operator and carry out a thorough and detailed investigation about the related properties.
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    Topology optimization subject to additive manufacturing constraints
    (Berlin ; Heidelberg : Springer, 2021) Ebeling-Rump, Moritz; Hömberg, Dietmar; Lasarzik, Robert; Petzold, Thomas
    In topology optimization the goal is to find the ideal material distribution in a domain subject to external forces. The structure is optimal if it has the highest possible stiffness. A volume constraint ensures filigree structures, which are regulated via a Ginzburg–Landau term. During 3D printing overhangs lead to instabilities. As a remedy an additive manufacturing constraint is added to the cost functional. First order optimality conditions are derived using a formal Lagrangian approach. With an Allen-Cahn interface propagation the optimization problem is solved iteratively. At a low computational cost the additive manufacturing constraint brings about support structures, which can be fine tuned according to demands and increase stability during the printing process.
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    Optimal Control Problems with Sparsity for Tumor Growth Models Involving Variational Inequalities
    (Dordrecht [u.a.] : Springer Science + Business Media, 2022) Colli, Pierluigi; Signori, Andrea; Sprekels, Jürgen
    This paper treats a distributed optimal control problem for a tumor growth model of Cahn–Hilliard type. The evolution of the tumor fraction is governed by a variational inequality corresponding to a double obstacle nonlinearity occurring in the associated potential. In addition, the control and state variables are nonlinearly coupled and, furthermore, the cost functional contains a nondifferentiable term like the L1-norm in order to include sparsity effects which is of utmost relevance, especially time sparsity, in the context of cancer therapies as applying a control to the system reflects in exposing the patient to an intensive medical treatment. To cope with the difficulties originating from the variational inequality in the state system, we employ the so-called deep quench approximation in which the convex part of the double obstacle potential is approximated by logarithmic functions. For such functions, first-order necessary conditions of optimality can be established by invoking recent results. We use these results to derive corresponding optimality conditions also for the double obstacle case, by deducing a variational inequality in terms of the associated adjoint state variables. The resulting variational inequality can be exploited to also obtain sparsity results for the optimal controls.