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- ItemOrthogonality of fluxes in general nonlinear reaction networks(Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2019) Renger, D.R.Michiel; Zimmer, JohannesWe consider the chemical reaction networks and study currents in these systems. Reviewing recent decomposition of rate functionals from large deviation theory for Markov processes, we adapt these results for reaction networks. In particular, we state a suitable generalisation of orthogonality of forces in these systems, and derive an inequality that bounds the free energy loss and Fisher information by the rate functional.