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Type: Report × Subject: evolution equations ×

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    Optimal control of a phase field system modelling tumor growth with chemotaxis and singular potentials
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2019) Colli, Pierluigi; Signori, Andrea; Sprekels, Jürgen
    A distributed optimal control problem for an extended model of phase field type for tumor growth is addressed. In this model, the chemotaxis effects are also taken into account. The control is realized by two control variables that design the dispensation of some drugs to the patient. The cost functional is of tracking type, whereas the potential setting has been kept quite general in order to allow regular and singular potentials to be considered. In this direction, some relaxation terms have been introduced in the system. We show the well-posedness of the state system, the Fréchet differentiability of the control-to-state operator in a suitable functional analytic framework, and, lastly, we characterize the first-order necessary conditions of optimality in terms of a variational inequality involving the adjoint variables.
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    Convergence rate estimates for Trotter product approximations of solution operators for non-autonomous Cauchy problems
    (Berlin : Weierstraß-Institut für Angewandte Analysis und Stochastik, 2016) Neidhardt, Hagen; Stephan, Artur; Zagrebnov, Valentin A.
    In the present paper we advocate the Howland-Evans approach to solution of the abstract non-autonomous Cauchy problem (non-ACP) in a separable Banach space X. The main idea is to reformulate this problem as an autonomous Cauchy problem (ACP) in a new Banach space Lp(I;X), p 2 [1;1), consisting of X-valued functions on the time-interval I. The fundamental observation is a one-to-one correspondence between solution operators (propagators) for a non-ACP and the corresponding evolution semigroups for ACP in Lp(I;X). We show that the latter also allows to apply a full power of the operatortheoretical methods to scrutinise the non-ACP including the proof of the Trotter product approximation formulae with operator-norm estimate of the rate of convergence. The paper extends and improves some recent results in this direction in particular for Hilbert spaces.