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- ItemOptical biosensors based on silicon-on-insulator ring resonators: A review(Basel : MDPI, 2019) Steglich, Patrick; Hülsemann, Marcel; Dietzel, Birgit; Mai, AndreasRecent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonators. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) system integration and measurement set-ups. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed. © 2019 by the authors.