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- ItemMultiscale Coupling of One-dimensional Vascular Models and Elastic Tissues(Dordrecht [u.a.] : Springer Science + Business Media B.V, 2021) Heltai, Luca; Caiazzo, Alfonso; Müller, Lucas O.We present a computational multiscale model for the efficient simulation of vascularized tissues, composed of an elastic three-dimensional matrix and a vascular network. The effect of blood vessel pressure on the elastic tissue is surrogated via hyper-singular forcing terms in the elasticity equations, which depend on the fluid pressure. In turn, the blood flow in vessels is treated as a one-dimensional network. Intravascular pressure and velocity are simulated using a high-order finite volume scheme, while the elasticity equations for the tissue are solved using a finite element method. This work addresses the feasibility and the potential of the proposed coupled multiscale model. In particular, we assess whether the multiscale model is able to reproduce the tissue response at the effective scale (of the order of millimeters) while modeling the vasculature at the microscale. We validate the multiscale method against a full scale (three-dimensional) model, where the fluid/tissue interface is fully discretized and treated as a Neumann boundary for the elasticity equation. Next, we present simulation results obtained with the proposed approach in a realistic scenario, demonstrating that the method can robustly and efficiently handle the one-way coupling between complex fluid microstructures and the elastic matrix. © 2021, The Author(s).
- ItemOn the convergence order of the finite element error in the kinetic energy for high Reynolds number incompressible flows(Amsterdam [u.a.] : Elsevier Science, 2021) García-Archilla, Bosco; John, Volker; Novo, JuliaThe kinetic energy of a flow is proportional to the square of the norm of the velocity. Given a sufficient regular velocity field and a velocity finite element space with polynomials of degree , then the best approximation error in is of order . In this survey, the available finite element error analysis for the velocity error in is reviewed, where is a final time. Since in practice the case of small viscosity coefficients or dominant convection is of particular interest, which may result in turbulent flows, robust error estimates are considered, i.e., estimates where the constant in the error bound does not depend on inverse powers of the viscosity coefficient. Methods for which robust estimates can be derived enable stable flow simulations for small viscosity coefficients on comparatively coarse grids, which is often the situation encountered in practice. To introduce stabilization techniques for the convection-dominated regime and tools used in the error analysis, evolutionary linear convection–diffusion equations are studied at the beginning. The main part of this survey considers robust finite element methods for the incompressible Navier–Stokes equations of order , , and for the velocity error in . All these methods are discussed in detail. In particular, a sketch of the proof for the error bound is given that explains the estimate of important terms which determine finally the order of convergence. Among them, there are methods for inf–sup stable pairs of finite element spaces as well as for pressure-stabilized discretizations. Numerical studies support the analytic results for several of these methods. In addition, methods are surveyed that behave in a robust way but for which only a non-robust error analysis is available. The conclusion of this survey is that the problem of whether or not there is a robust method with optimal convergence order for the kinetic energy is still open.