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Gradients of Al/Al2O3 nanostructures for screening mesenchymal stem cell proliferation and differentiation

2013, Veith, Michael, Dufloux, Cécile, Ghaemi, Soraya Rasi, Cenk, Aktas, Voelcker, Nicolas H.

By decomposing a molecular precursor we fabricated a novel surface based on an aluminium/aluminiumoxide composite incorporating nanotopography gradient to address high-throughput and fast analysis method for studying stem cell differentiation by nanostructures. Depending on the topography of the nanostructures, mesenchymal stem cells exhibit a diverse proliferation and differentiation behavior.