2017, Reddy G., Upendar, Liu, Jingjing, Hoffmann, Patrick, Steinmetzer, Johannes, Görls, Helmar, Kupfer, Stephan, Askes, Sven H. C., Neugebauer, Ute, Gräfe, Stefanie, Schiller, Alexander

Carbon monoxide (CO) is known for its multifaceted role in human physiology, and molecules that release CO in a controlled way have been proposed as therapeutic drugs. In this work, a light-responsive CO-releasing molecule (CORM-Dabsyl) showed a strong colourimetric response upon photochemical CO-release, owing to the tight conjugation of a Mn(i) tricarbonyl centre to a dabsyl chromophoric ligand (L). Whereas the complex was very stable in the dark in nitrogen-purged aqueous media, CO-release was effectively triggered using 405 nm irradiation. CORM-Dabsyl, L and the inactive product iCORM-Dabsyl have been investigated by DFT and TD-DFT calculations. Only mild toxicity of CORM-Dabsyl was observed against LX-2 and HepaRG® human cell lines (IC50 ∼ 30 μM). Finally, to develop a CO storage and release material that is readily applicable to therapeutic situations, CORM-Dabsyl was loaded on low-cost and easily disposable paper strips, from which the light triggered CO-release was conveniently visible with the naked eye.

2011, Müller, M., Keßler, B., Fröhlich, J., Poeschla, S., Torger, B.

In this contribution we outline polyelectrolyte (PEL) complex (PEC) nanoparticles, prepared by mixing solutions of the low cost PEL components poly(ethyleneimine) (PEI) and poly(acrylic acid) (PAC). It was found, that the size and internal structure of PEI/PAC particles can be regulated by process, media and structural parameters. Especially, mixing order, mixing ratio, PEL concentration, pH and molecular weight, were found to be sensible parameters to regulate the size (diameter) of spherical PEI/PAC nanoparticles, in the range between 80-1,000 nm, in a defined way. Finally, applications of dispersed PEI/PAC particles as additives for the paper making process, as well as for drug delivery, are outlined. PEI/PAC nanoparticles mixed directly on model cellulose film showed a higher adsorption level applying the mixing order 1. PAC 2. PEI compared to 1. PEI 2. PAC. Surface bound PEI/PAC nanoparticles were found to release a model drug compound and to stay immobilized due to the contact with the aqueous release medium.

2021, Mendes, Rafael G., Ta, Huy Q., Yang, Xiaoqin, Bachmatiuk, Alicja, Praus, Petr, Mamakhel, Aref, Iversen, Bo B., Su, Ren, Gemming, Thomas, Rümmeli, Mark H.

Two-dimensional polymeric graphitic carbon nitride (g-C3N4) is a low-cost material with versatile properties that can be enhanced by the introduction of dopant atoms and by changing the degree of polymerization/stoichiometry, which offers significant benefits for numerous applications. Herein, we investigate the stability of g-C3N4 under electron beam irradiation inside a transmission electron microscope operating at different electron acceleration voltages. Our findings indicate that the degradation of g-C3N4 occurs with N species preferentially removed over C species. However, the precise nitrogen group from which N is removed from g-C3N4 (C–N–C, [double bond, length as m-dash]NH or –NH2) is unclear. Moreover, the rate of degradation increases with decreasing electron acceleration voltage, suggesting that inelastic scattering events (radiolysis) dominate over elastic events (knock-on damage). The rate of degradation by removing N atoms is also sensitive to the current density. Hence, we demonstrate that both the electron acceleration voltage and the current density are parameters with which one can use to control the stoichiometry. Moreover, as N species were preferentially removed, the d-spacing of the carbon nitride structure increased. These findings provide a deeper understanding of g-C3N4.

2020, Kang, D.J., Jüttke, Y., González-García, L., Escudero, A., Haft, M., Kraus, T.

Conductive inkjet printing with metal nanoparticles is irreversible because the particles are sintered into a continuous metal film. The resulting structures are difficult to remove or repair and prone to cracking. Here, a hybrid ink is used to obviate the sintering step and print interconnected particle networks that become highly conductive immediately after drying. It is shown that reversible conductive printing is possible on low-cost cardboard samples after applying standard paper industry coats that are adapted in terms of surface energy and porosity. The conductivity of the printed films approaches that of sintered standard inks on the same substrate, but the mobility of the hybrid particle film makes them less sensitive to cracks during bending and folding of the substrate. Damages that occur can be partially repaired by wetting the film such that particle mobility is increased and particles move to bridge insulating gaps in the film. It is demonstrated that the conductive material can be recovered from the cardboard at the end of its life time and be redispersed to recycle the particles and reuse them in conductive inks.

2009, Bauer, N., Edenhofer, O., Leimbach, M.

Endogenous technology scenarios for meeting low stabilization CO2 targets are derived in this study and assessed regarding emission reductions and mitigation costs. The aim is to indentify the most important technology options for achieving low stabilization targets. The significance of an option is indicated by its achieved emission reduction and the mitigation cost increase, if this option were not available. Quantitative results are computed using a global multi-regional hard-linked hybrid model that integrates the economy, the energy sector and the climate system. The model endogenously determines the optimal deployment of technologies subject to a constraint on climate change. The alternative options in the energy sector comprise the most important mitigation technologies: renewables, biomass, nuclear, carbon capture and sequestration (CCS), and biomass with CCS as well as energy efficiency improvements. The results indicate that the availability of CCS technologies and espec. biomass with CCS is highly desirable for achieving low stabilization goals at low costs. The option of nuclear energy is different: although it could play an important role in the primary energy mix, mitigation costs would only mildly increase, if it could not be expanded. Therefore, in order to promote prudent climate change mitigation goals, support of CCS technologies reduces the costs and-thus-is desirable from a social point of view. © 2009 Elsevier Ltd. All rights reserved.