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Magnetic Micromotors for Multiple Motile Sperm Cells Capture, Transport, and Enzymatic Release

2020, Xu, H., Medina-Sánchez, M., Schmidt, O.G.

An integrated system combining a magnetically-driven micromotor and a synthetized protein-based hyaluronic acid (HA) microflake is presented for the in situ selection and transport of multiple motile sperm cells (ca. 50). The system appeals for targeted sperm delivery in the reproductive system to assist fertilization or to deliver drugs. The binding mechanism between the HA microflake and sperm relies on the interactions between HA and the corresponding sperm HA receptors. Once sperm are captured within the HA microflake, the assembly is trapped and transported by a magnetically-driven helical microcarrier. The trapping of the sperm-microflake occurs by a local vortex induced by the microcarrier during rotation-translation under a rotating magnetic field. After transport, the microflake is enzymatically hydrolyzed by local proteases, allowing sperm to escape and finally reach the target location. This cargo-delivery system represents a new concept to transport not only multiple motile sperm but also other actively moving biological cargoes.

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Magnetic tornadoes and chromospheric swirls – Definition and classification

2013, Wedemeyer, Sven, Scullion, Eamon, Steiner, Oskar, de la Cruz Rodriguez, Jaime, Rouppe van der Voort, Luc

Chromospheric swirls are the observational signatures of rotating magnetic field structures in the solar atmosphere, also known as magnetic tornadoes. Swirls appear as dark rotating features in the core of the spectral line of singly ionized calcium at a wavelength of 854.2 nm. This signature can be very subtle and difficult to detect given the dynamic changes in the solar chromosphere. Important steps towards a systematic and objective detection method are the compilation and characterization of a statistically significant sample of observed and simulated chromospheric swirls. Here, we provide a more exact definition of the chromospheric swirl phenomenon and also present a first morphological classification of swirls with three types: (I) Ring, (II) Split, (III) Spiral. We also discuss the nature of the magnetic field structures connected to tornadoes and the influence of limited spatial resolution on the appearance of their photospheric footpoints.