An epidemic CC1-MRSA-IV clone yields false-negative test results in molecular MRSA identification assays: a note of caution, Austria, Germany, Ireland, 2020

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dc.bibliographicCitation.issue25eng
dc.bibliographicCitation.volume25eng
dc.contributor.authorMonecke, Stefan
dc.contributor.authorKönig, Elisabeth
dc.contributor.authorEarls, Megan R.
dc.contributor.authorLeitner, Eva
dc.contributor.authorMüller, Elke
dc.contributor.authorWagner, Gabriel E.
dc.contributor.authorPoitz, David M.
dc.contributor.authorJatzwauk, Lutz
dc.contributor.authorVremerǎ, Teodora
dc.contributor.authorDorneanu, Olivia S.
dc.contributor.authorSimbeck, Alexandra
dc.contributor.authorAmbrosch, Andreas
dc.contributor.authorZollner-Schwetz, Ines
dc.contributor.authorKrause, Robert
dc.contributor.authorRuppitsch, Werner
dc.contributor.authorSchneider-Brachert, Wulf
dc.contributor.authorColeman, David C.
dc.contributor.authorSteinmetz, Ivo
dc.contributor.authorEhricht, Ralf
dc.date.accessioned2021-10-19T11:55:27Z
dc.date.available2021-10-19T11:55:27Z
dc.date.issued2020
dc.description.abstractWe investigated why a clinical meticillin-resistant Staphylococcus aureus (MRSA) isolate yielded false-negative results with some commercial PCR tests for MRSA detection. We found that an epidemic European CC1-MRSA-IV clone generally exhibits this behaviour. The failure of the assays was attributable to a large insertion in the orfX/SCCmec integration site. To ensure the reliability of molecular MRSA tests, it is vital to monitor emergence of new SCCmec types and junction sites.eng
dc.description.versionpublishedVersioneng
dc.identifier.urihttps://oa.tib.eu/renate/handle/123456789/7049
dc.identifier.urihttps://doi.org/10.34657/6096
dc.language.isoengeng
dc.publisherStockholm : European Centre for Disease Prevention and Controleng
dc.relation.doihttps://doi.org/10.2807/1560-7917.ES.2020.25.25.2000929
dc.relation.essn1560-7917
dc.relation.ispartofseriesEurosurveillance 25 (2020), Nr. 25eng
dc.relation.issn1025-496X
dc.rights.licenseCC BY 4.0 Unportedeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/eng
dc.subjectBD MAX, next generation sequencingeng
dc.subjectCC1-MRSA-IVeng
dc.subjectCepheid GenXperteng
dc.subjectcommercial PCReng
dc.subjectStaphylococcieng
dc.subjectStaphylococcus aureuseng
dc.subject.ddc610eng
dc.titleAn epidemic CC1-MRSA-IV clone yields false-negative test results in molecular MRSA identification assays: a note of caution, Austria, Germany, Ireland, 2020eng
dc.typearticleeng
dc.typeTexteng
dcterms.bibliographicCitation.journalTitleEurosurveillanceeng
tib.accessRightsopenAccesseng
wgl.contributorIPHTeng
wgl.subjectMedizin, Gesundheiteng
wgl.typeZeitschriftenartikeleng
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