Photoactivatable Hsp47: A tool to control and regulate collagen secretion & assembly
| dc.contributor.author | Khan, Essak | |
| dc.contributor.author | Sankaran, Shrikrishnan | |
| dc.contributor.author | Paez, Julieta | |
| dc.contributor.author | Muth, Christina | |
| dc.contributor.author | Han, Mitchell | |
| dc.contributor.author | del Campo, Aránzazu | |
| dc.date.available | 2019-06-28T13:59:04Z | |
| dc.date.issued | 2018 | |
| dc.description.abstract | Hsp47 is a chaperone protein with a fundamental role in the folding, stability and intracellular transport of procollagen triple helices. A light-responsive Hsp47 recombinant protein, engineered to control in situ the production and assembly of cellular collagen is here demonstrated. This novel light-driven tool enables unprecedented fundamental studies of collagen biosynthesis and associated diseases. | |
| dc.description.version | publishedVersion | eng |
| dc.format | application/pdf | |
| dc.identifier.uri | https://doi.org/10.34657/579 | |
| dc.identifier.uri | https://oa.tib.eu/renate/handle/123456789/4628 | |
| dc.language.iso | eng | eng |
| dc.publisher | ChemRxiv | |
| dc.relation.doi | https://doi.org/10.26434/chemrxiv.6964703.v1 | |
| dc.relation.ispartofseries | ChemRxiv | eng |
| dc.rights.license | CC BY-NC-ND 4.0 Unported | eng |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | eng |
| dc.subject.ddc | 540 | |
| dc.title | Photoactivatable Hsp47: A tool to control and regulate collagen secretion & assembly | |
| dc.type | article | eng |
| dc.type | Text | eng |
| dcterms.bibliographicCitation.journalTitle | ChemRxiv | eng |
| tib.accessRights | openAccess | eng |
| wgl.contributor | INM | eng |
| wgl.subject | Chemie | eng |
| wgl.type | Zeitschriftenartikel | eng |
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