Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries

dc.bibliographicCitation.firstPagem108
dc.bibliographicCitation.volume368
dc.contributor.authorVicedo-Cabrera, Ana M.
dc.contributor.authorSera, Francesco
dc.contributor.authorLiu, Cong
dc.contributor.authorArmstrong, Ben
dc.contributor.authorMilojevic, Ai
dc.contributor.authorGuo, Yuming
dc.contributor.authorTong, Shilu
dc.contributor.authorLavigne, Eric
dc.contributor.authorKyselý, Jan
dc.contributor.authorUrban, Aleš
dc.contributor.authorOrru, Hans
dc.contributor.authorIndermitte, Ene
dc.contributor.authorPascal, Mathilde
dc.contributor.authorHuber, Veronika
dc.contributor.authorSchneider, Alexandra
dc.contributor.authorKatsouyanni, Klea
dc.contributor.authorSamoli, Evangelia
dc.contributor.authorStafoggia, Massimo
dc.contributor.authorScortichini, Matteo
dc.contributor.authorHashizume, Masahiro
dc.contributor.authorHonda, Yasushi
dc.contributor.authorNg, Chris Fook Sheng
dc.contributor.authorHurtado-Diaz, Magali
dc.contributor.authorCruz, Julio
dc.contributor.authorSilva, Susana
dc.contributor.authorMadureira, Joana
dc.contributor.authorScovronick, Noah
dc.contributor.authorGarland, Rebecca M.
dc.contributor.authorKim, Ho
dc.contributor.authorTobias, Aurelio
dc.contributor.authorÍñiguez, Carmen
dc.contributor.authorForsberg, Bertil
dc.contributor.authorÅström, Christofer
dc.contributor.authorRagettli, Martina S.
dc.contributor.authorRöösli, Martin
dc.contributor.authorGuo, Yue-Liang Leon
dc.contributor.authorChen, Bing-Yu
dc.contributor.authorZanobetti, Antonella
dc.contributor.authorSchwartz, Joel
dc.contributor.authorBell, Michelle L.
dc.contributor.authorKan, Haidong
dc.contributor.authorGasparrini, Antonio
dc.date.accessioned2022-12-09T07:11:19Z
dc.date.available2022-12-09T07:11:19Z
dc.date.issued2020
dc.description.abstractObjective To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. Design Two stage time series analysis. Setting 406 cities in 20 countries, with overlapping periods between 1985 and 2015, collected from the database of Multi-City Multi-Country Collaborative Research Network. Population Deaths for all causes or for external causes only registered in each city within the study period. Main outcome measures Daily total mortality (all or non-external causes only). Results A total of 45 165 171 deaths were analysed in the 406 cities. On average, a 10 μg/m 3 increase in ozone during the current and previous day was associated with an overall relative risk of mortality of 1.0018 (95% confidence interval 1.0012 to 1.0024). Some heterogeneity was found across countries, with estimates ranging from greater than 1.0020 in the United Kingdom, South Africa, Estonia, and Canada to less than 1.0008 in Mexico and Spain. Short term excess mortality in association with exposure to ozone higher than maximum background levels (70 μg/m 3) was 0.26% (95% confidence interval 0.24% to 0.28%), corresponding to 8203 annual excess deaths (95% confidence interval 3525 to 12 840) across the 406 cities studied. The excess remained at 0.20% (0.18% to 0.22%) when restricting to days above the WHO guideline (100 μg/m 3), corresponding to 6262 annual excess deaths (1413 to 11 065). Above more lenient thresholds for air quality standards in Europe, America, and China, excess mortality was 0.14%, 0.09%, and 0.05%, respectively. Conclusions Results suggest that ozone related mortality could be potentially reduced under stricter air quality standards. These findings have relevance for the implementation of efficient clean air interventions and mitigation strategies designed within national and international climate policies. © Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to.eng
dc.description.versionpublishedVersion
dc.identifier.urihttps://oa.tib.eu/renate/handle/123456789/10571
dc.identifier.urihttp://dx.doi.org/10.34657/9607
dc.language.isoeng
dc.publisherLondon : BMJ Publ. Group
dc.relation.doihttps://doi.org/10.1136/bmj.m108
dc.relation.essn1756-1833
dc.relation.ispartofseriesThe BMJ 368 (2020)eng
dc.rights.licenseCC BY 4.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAir Pollutioneng
dc.subjectCitieseng
dc.subjectClimate Changeeng
dc.subjectEnvironmental Exposureeng
dc.subjectEnvironmental Policyeng
dc.subjectGlobal Healtheng
dc.subjectHumanseng
dc.subjectInternational Cooperationeng
dc.subjectMortalityeng
dc.subjectOzoneeng
dc.subjectSeasonseng
dc.subject.ddc610
dc.titleShort term association between ozone and mortality: global two stage time series study in 406 locations in 20 countrieseng
dc.typearticle
dc.typeText
dcterms.bibliographicCitation.journalTitleThe BMJ
tib.accessRightsopenAccess
wgl.contributorPIK
wgl.contributorIAP
wgl.subjectMedizin, Gesundheitger
wgl.typeZeitschriftenartikelger
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