Comparison of bacteria in different metabolic states by micro-Raman spectroscopy

dc.bibliographicCitation.date2023
dc.bibliographicCitation.firstPage134831
dc.bibliographicCitation.journalTitleJournal of molecular structureeng
dc.bibliographicCitation.volume1277
dc.contributor.authorShen, Haodong
dc.contributor.authorRösch, Petra
dc.contributor.authorThieme, Lara
dc.contributor.authorPletz, Mathias W.
dc.contributor.authorPopp, Jürgen
dc.date.accessioned2023-02-22T06:09:18Z
dc.date.available2023-02-22T06:09:18Z
dc.date.issued2022
dc.description.abstractIt was shown that several metabolic states of bacteria with various characteristics such as chemical composition participate in the formation of biofilms. To study the connections and differences among different bacterial metabolic states, five species of bacteria in exponential phase, stationary phase and biofilm have been compared and investigated by micro-Raman spectroscopy. The spectral differences between different metabolic states showed that the chemical composition varied among those metabolic states. Moreover, as can be shown by the spectral differences and principal components (PCs), different species and strains of bacteria behave differently. Furthermore, a principal component analysis (PCA) combined with support vector machines (SVM) was applied to distinguish species of bacteria within the same metabolic states. Our study provides valuable data for the comparison of bacteria between different metabolic states utilizing micro-Raman spectroscopy in combination with chemometrics models.eng
dc.description.versionpublishedVersioneng
dc.identifier.urihttps://oa.tib.eu/renate/handle/123456789/11477
dc.identifier.urihttp://dx.doi.org/10.34657/10510
dc.language.isoeng
dc.publisherNew York, NY [u.a.] : Elsevier
dc.relation.doihttps://doi.org/10.1016/j.molstruc.2022.134831
dc.relation.essn0022-2860
dc.rights.licenseCC BY 4.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subject.ddc540
dc.subject.otherBiofilmeng
dc.subject.otherMetabolic stateseng
dc.subject.otherMicro-Raman spectroscopyeng
dc.subject.otherPlanktoniceng
dc.titleComparison of bacteria in different metabolic states by micro-Raman spectroscopyeng
dc.typeArticleeng
dc.typeTexteng
tib.accessRightsopenAccess
wgl.contributorIPHT
wgl.subjectMedizin, Gesundheitger
wgl.typeZeitschriftenartikelger
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