A novel patch micro electrode array for sensing ionic membrane currents
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Date
2011
Volume
25
Issue
Journal
Series Titel
Book Title
Publisher
Amsterdam [u.a.] : Elsevier
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Abstract
Ionic membrane currents play an important role during regeneration of nerve cells, embryonic development and wound healing processes. Measuring the intracellular ion currents across the cell membrane is important in understanding the cellular functions related to the ion activities. A novel patch micro electrode array (p-MEA) for measuring the ionic membrane currents without poisoning the cells due to emitting metal ions is described in this paper. Results on biocompatibility of the device are presented. We discuss the fabrication and working principle of p-MEA.
Description
Keywords
3T3 Fibroblast cells, Ionic membrane currents, Micro electrode array, Patch clamp, Cellular function, Embryonic development, Fibroblast cells, Ion activities, Ion currents, Ionic membranes, Microelectrode array, Patch clamp, Working principles, Wound healing process, Biocompatibility, Cell culture, Cell membranes, Metal ions, Neurons, Electrophysiology
Citation
Aryasomayajula, A., Perike, S., Hensel, R., Posseckardt, J., Gerlach, G., & Funk, R. H. W. (2011). A novel patch micro electrode array for sensing ionic membrane currents. 25. https://doi.org//10.1016/j.proeng.2011.12.339
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License
CC BY-NC-ND 3.0 Unported