Activation of perfluoroalkyl iodides by anions: extending the scope of halogen bond activation to C(sp3)-H amidation, C(sp2)-H iodination, and perfluoroalkylation reactions
dc.bibliographicCitation.firstPage | 1732 | |
dc.bibliographicCitation.issue | 7 | |
dc.bibliographicCitation.lastPage | 1741 | |
dc.bibliographicCitation.volume | 14 | |
dc.contributor.author | Wang, Yaxin | |
dc.contributor.author | Cao, Zehui | |
dc.contributor.author | He, Qin | |
dc.contributor.author | Huang, Xin | |
dc.contributor.author | Liu, Jiaxi | |
dc.contributor.author | Neumann, Helfried | |
dc.contributor.author | Chen, Gong | |
dc.contributor.author | Beller, Matthias | |
dc.date.accessioned | 2023-06-02T15:00:32Z | |
dc.date.available | 2023-06-02T15:00:32Z | |
dc.date.issued | 2023 | |
dc.description.abstract | A simple, efficient, and convenient activation of perfluoroalkyl iodides by tBuONa or KOH, without expensive photo- or transition metal catalysts, allows the promotion of versatile a-sp3 C-H amidation reactions of alkyl ethers and benzylic hydrocarbons, C-H iodination of heteroaryl compounds, and perfluoroalkylations of electron-rich p bonds. Mechanistic studies show that these novel protocols are based on the halogen bond interaction between perfluoroalkyl iodides and tBuONa or KOH, which promote homolysis of perfluoroalkyl iodides under mild conditions. | eng |
dc.description.version | publishedVersion | eng |
dc.identifier.uri | https://oa.tib.eu/renate/handle/123456789/12252 | |
dc.identifier.uri | http://dx.doi.org/10.34657/11284 | |
dc.language.iso | eng | |
dc.publisher | Cambridge : RSC Publishing | |
dc.relation.doi | https://doi.org/10.1039/d2sc06145g | |
dc.relation.essn | 2041-6539 | |
dc.relation.ispartofseries | Chemical Science 14 (2023), Nr. 7 | eng |
dc.relation.issn | 2041-6520 | |
dc.rights.license | CC BY-NC 3.0 Unported | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/3.0 | |
dc.subject | homolytic aromatic-substitution | eng |
dc.subject | transfer radical-addition | eng |
dc.subject | c-h iodination | eng |
dc.subject | photoredox catalysis | eng |
dc.subject | aryl halides | eng |
dc.subject | trifluoromethylation | eng |
dc.subject | organocatalysis | eng |
dc.subject | thermodynamics | eng |
dc.subject | heterocycles | eng |
dc.subject | heteroatom | eng |
dc.subject.ddc | 540 | |
dc.title | Activation of perfluoroalkyl iodides by anions: extending the scope of halogen bond activation to C(sp3)-H amidation, C(sp2)-H iodination, and perfluoroalkylation reactions | eng |
dc.type | article | |
dc.type | Text | |
dcterms.bibliographicCitation.journalTitle | Chemical Science | |
tib.accessRights | openAccess | |
wgl.contributor | LIKAT | |
wgl.subject | Chemie | ger |
wgl.type | Zeitschriftenartikel | ger |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- 09Activation-of-perfluoroalkyl.pdf
- Size:
- 2.19 MB
- Format:
- Adobe Portable Document Format
- Description: