Identification of Eps15 as antigen recognized by the monoclonal antibodies aa2 and ab52 of the wuerzburg hybridoma library against Drosophila brain
dc.bibliographicCitation.issue | 12 | eng |
dc.bibliographicCitation.journalTitle | PLOS ONE | eng |
dc.bibliographicCitation.volume | 6 | |
dc.contributor.author | Halder, Partho | |
dc.contributor.author | Chen, Yi-chun | |
dc.contributor.author | Brauckhoff, Janine | |
dc.contributor.author | Hofbauer, Alois | |
dc.contributor.author | Dabauvalle, Marie-Christine | |
dc.contributor.author | Lewandrowski, Urs | |
dc.contributor.author | Winkler, Christiane | |
dc.contributor.author | Sickmann, Albert | |
dc.contributor.author | Buchner, Erich | |
dc.date.accessioned | 2018-02-21T22:05:11Z | |
dc.date.available | 2019-06-28T08:33:10Z | |
dc.date.issued | 2011 | |
dc.description.abstract | The Wuerzburg Hybridoma Library against the Drosophila brain represents a collection of around 200 monoclonal antibodies that bind to specific structures in the Drosophila brain. Here we describe the immunohistochemical staining patterns, the Western blot signals of one- and two-dimensional electrophoretic separation, and the mass spectrometric characterization of the target protein candidates recognized by the monoclonal antibodies aa2 and ab52 from the library. Analysis of a mutant of a candidate gene identified the Drosophila homolog of the Epidermal growth factor receptor Pathway Substrate clone 15 (Eps15) as the antigen for these two antibodies. | eng |
dc.description.version | publishedVersion | eng |
dc.format | application/pdf | |
dc.identifier.uri | https://doi.org/10.34657/1746 | |
dc.identifier.uri | https://oa.tib.eu/renate/handle/123456789/3690 | |
dc.language.iso | eng | eng |
dc.publisher | San Francisco, CA : Public Library of Science | eng |
dc.relation.doi | https://doi.org/10.1371/journal.pone.0029352 | |
dc.rights.license | CC BY 4.0 Unported | eng |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | eng |
dc.subject.ddc | 610 | eng |
dc.subject.other | Antibodies | eng |
dc.subject.other | Monoclonal | eng |
dc.subject.other | Antigens | eng |
dc.subject.other | Drosophila Proteins | eng |
dc.subject.other | Eps15 protein | eng |
dc.subject.other | Drosophila | eng |
dc.subject.other | Nerve Tissue Proteins | eng |
dc.title | Identification of Eps15 as antigen recognized by the monoclonal antibodies aa2 and ab52 of the wuerzburg hybridoma library against Drosophila brain | eng |
dc.type | Article | eng |
dc.type | Text | eng |
tib.accessRights | openAccess | eng |
wgl.contributor | ISAS | eng |
wgl.subject | Medizin, Gesundheit | eng |
wgl.type | Zeitschriftenartikel | eng |
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