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    Non-thermal plasma treatment induces MAPK signaling in human monocytes
    (Berlin : de Gruyter, 2014) Bundscherer, Lena; Nagel, Stefanie; Hasse, Sybille; Tresp, Helena; Wende, Kristian; Walther, Reinhard; Reuter, Stephan; Weltmann, Klaus-Dieter; Masur, Kai; Lindequist, Ulrike
    The application of non-thermal atmospheric pressure plasma raises a hope for the new wound healing strategies. Next to its antibacterial effect it is known to stimulate skin cells. However, monocytes are also needed for the complex process of a wound healing. This study investigates the impact of plasma on the intracellular signaling events in the primary human monocytes. The proliferative MEK-ERK (MAPK/ERK kinase-extracellular signal-regulated kinase) pathway was activated by short plasma treatment times. In contrast, an induction of the apoptotic JNK (c-Jun N-terminal kinase) cascade as well as activation of caspase 3 were observed after long plasma exposure. These findings indicate that monocytes can be differentially stimulated by plasma treatment and may contribute to the proper wound recovery.
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    Studies on the Electrical Behaviour and Removal of Toluene with a Dielectric Barrier Discharge
    (Berlin : de Gruyter, 2014) Schmidt, Michael; Schiorlin, Milko; Brandenburg, Ronny
    This contribution attempts to establish an easy-to-apply non-thermal plasma reactor for efficient toluene removal. Derived from the already established knowledge of the so called Dielectric Barrier Discharge (DBD) Stack Reactor a new model reactor was used in this work. The DBD Stack Reactor is a multi-elements reactor but in this work only one stack element was used to investigate the efficiency and efficacy of toluene removal. In case of reliable results the scalability process for industrial application is already well known. Therefore, laboratory experiments were conducted in dry and wet synthetic air with an admixture of 50 ppm toluene. Along with the toluene removal process the electrical behaviour of the discharge configuration was investigated. It was found that the electrical capacitance of the dielectric barrier changes with variations of the operating voltage. This could be due to the changes in the area of the dielectric barrier which is covered with plasma. Additionally, it was found that the power input into the plasma, at a fixed operating voltage, is proportional to the frequency, which is in agreement with the literature.Regarding the decomposition process, the total removal of toluene was achieved at specific input energy densities of 55 J L-1 under dry conditions and 110 J L-1 under wet conditions. The toluene removal was accompanied by the production of nitric acid (dry conditions) and formic acid (wet conditions). The latter suggested a combination of the plasma reactor with a water scrubber as an approach for total removal of pollutant molecules.