Noise-Aided Logic in an Electronic Analog of Synthetic Genetic Networks

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Date
2013
Volume
8
Issue
10
Journal
Series Titel
Book Title
Publisher
San Francisco, CA : Public Library of Science (PLoS)
Abstract

We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit allowing for robust logic operations in an optimal window of noise. Namely, the input-output characteristics of a logic gate is reproduced faithfully under moderate noise, which is a manifestation of the phenomenon known as Logical Stochastic Resonance. The two dynamical variables in the system yield complementary logic behaviour simultaneously. The system is easily morphed from AND/NAND to OR/NOR logic.

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Keywords
article, electronic analog, electronics, experimental study, genetic model, logic, mathematical computing, mathematical model, noise, noise aided logic, noise measurement, promoter region, repressor gene, stochastic model, system analysis, Gene Regulatory Networks
Citation
Hellen, E. H., Dana, S. K., Kurths, J., Kehler, E., & Sinha, S. (2013). Noise-Aided Logic in an Electronic Analog of Synthetic Genetic Networks. 8(10). https://doi.org//10.1371/journal.pone.0076032
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License
CC BY 3.0 Unported