High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation
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Date
2020
Volume
50
Issue
12
Journal
Series Titel
Book Title
Publisher
Hoboken, NJ : Wiley
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Abstract
In CTLs: High glucose‐culture enhances thapsigargin‐induced SOCE but decreases target recognition‐induced Ca2+ influx. High glucose‐culture regulates expression of ORAIs and STIMs without affecting glucose uptake. More high glucose‐cultured CTLs are prone to necrosis after execution of killing.
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Keywords
cytotoxic T lymphocytes, glucose, killing process
Citation
Zou, H., Yang, W., Schwär, G., Zhao, R., Alansary, D., Yin, D., et al. (2020). High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation. 50(12). https://doi.org//10.1002/eji.202048577
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CC BY-NC 4.0 Unported