Novel monomers in radical ring-opening polymerisation for biodegradable and pH responsive nanoparticles

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dc.bibliographicCitation.firstPage5285eng
dc.bibliographicCitation.issue39eng
dc.bibliographicCitation.lastPage5288eng
dc.bibliographicCitation.volume10eng
dc.contributor.authorFolini, Jenny
dc.contributor.authorHuang, Chao-Hung
dc.contributor.authorAnderson, James C.
dc.contributor.authorMeier, Wolfgang P.
dc.contributor.authorGaitzsch, Jens
dc.date.accessioned2021-12-13T07:34:25Z
dc.date.available2021-12-13T07:34:25Z
dc.date.issued2019
dc.description.abstractResponsive and biodegradable nanoparticles are essential for functional drug delivery systems. We herein report the first pH sensitive polyester from radical ring-opening polymerisation of novel amine-bearing cyclic ketene acetals (CKAs). The CKAs were synthesised via an intermediate carbonate and the resulting polyesters showed a pKa around pH 6. Together with an initial application in biodegradable nanoparticles, they open the pathway for a new generation of functional polyesters.eng
dc.description.versionpublishedVersioneng
dc.identifier.urihttps://oa.tib.eu/renate/handle/123456789/7694
dc.identifier.urihttps://doi.org/10.34657/6741
dc.language.isoengeng
dc.publisherBrookfield, Conn. : Society of Plastic Engineerseng
dc.relation.doihttps://doi.org/10.1039/c9py01103j
dc.relation.essn1759-9962
dc.relation.ispartofseriesPolymer chemistry 10 (2019), Nr. 39eng
dc.rights.licenseCC BY-NC 3.0 Unportedeng
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/eng
dc.subjectBiodegradable polymerseng
dc.subjectNanoparticleseng
dc.subjectPolyesterseng
dc.subjectPolymerizationeng
dc.subjectBiodegradable nanoparticleeng
dc.subjectCyclic ketene acetalseng
dc.subjectDrug delivery systemeng
dc.subjectpH sensitiveeng
dc.subjectPH-responsiveeng
dc.subjectSynthesisedeng
dc.subjectDrug deliveryeng
dc.subject.ddc540eng
dc.titleNovel monomers in radical ring-opening polymerisation for biodegradable and pH responsive nanoparticleseng
dc.typearticleeng
dc.typeTexteng
dcterms.bibliographicCitation.journalTitlePolymer chemistryeng
tib.accessRightsopenAccesseng
wgl.contributorIPFeng
wgl.subjectChemieeng
wgl.typeZeitschriftenartikeleng
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