High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation

In CTLs: High glucose‐culture enhances thapsigargin‐induced SOCE but decreases target recognition‐induced Ca2+ influx. High glucose‐culture regulates expression of ORAIs and STIMs without affecting glucose uptake. More high glucose‐cultured CTLs are prone to necrosis after execution of killing.

URI

https://doi.org/10.34657/4664
https://oa.tib.eu/renate/handle/123456789/6035

Citation

Zou, H., Yang, W., Schwär, G., Zhao, R., Alansary, D., Yin, D., et al. (2020). High glucose distinctively regulates Ca2+ influx in cytotoxic T lymphocytes upon target recognition and thapsigargin stimulation (Hoboken, NJ : Wiley). Hoboken, NJ : Wiley. https://doi.org//10.1002/eji.202048577

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Biowissenschaften

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CC BY-NC 4.0 Unported

https://creativecommons.org/licenses/by-nc/4.0/

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